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Vonoprazan, Amoxicillin and Levofloxacin — Competitive Intelligence Brief
phase 3
Potassium-competitive acid blocker (P-CAB)
H+/K+ ATPase
Gastroenterology
Small molecule
Live · refreshed every 30 min
Target snapshot
Vonoprazan, Amoxicillin and Levofloxacin (Vonoprazan, Amoxicillin and Levofloxacin) — Ain Shams University. Vonoprazan is a potassium-competitive acid blocker (P-CAB) that inhibits gastric acid secretion by blocking the H+/K+ ATPase enzyme in the parietal cells of the stomach.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Vonoprazan, Amoxicillin and Levofloxacin TARGET | Vonoprazan, Amoxicillin and Levofloxacin | Ain Shams University | phase 3 | Potassium-competitive acid blocker (P-CAB) | H+/K+ ATPase | |
| Vonoprazan Tablets | Vonoprazan Tablets | Humanis Saglık Anonim Sirketi | marketed | Potassium-competitive acid blocker (P-CAB) | H+/K+-ATPase (proton pump) | |
| Tegoprazan 50 mg, tablets, orally, qd | Tegoprazan 50 mg, tablets, orally, qd | Zhang Xiaofeng,MD | marketed | Potassium-competitive acid blocker (P-CAB) | H+/K+-ATPase | |
| Tegoprazan 50 mg | Tegoprazan 50 mg | First People's Hospital of Hangzhou | marketed | Potassium-Competitive Acid Blocker (P-CAB) | H+/K+-ATPase | |
| Fexuprazan Hydrochloride | Fexuprazan Hydrochloride | Daewoong Pharmaceutical Co. LTD. | marketed | Potassium-competitive acid blocker (P-CAB) | H+/K+-ATPase (proton pump) | |
| Linaprazan glurate - Low dose | Linaprazan glurate - Low dose | Cinclus Pharma Holding AB | phase 3 | Potassium-competitive acid blocker (P-CAB) | H+/K+-ATPase (gastric proton pump) | |
| Linaprazan glurate - High dose | Linaprazan glurate - High dose | Cinclus Pharma Holding AB | phase 3 | Potassium-competitive acid blocker (P-CAB) | H+/K+-ATPase (gastric proton pump) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Potassium-competitive acid blocker (P-CAB) class)
- Cinclus Pharma Holding AB · 2 drugs in this class
- Aga Khan University · 1 drug in this class
- Ain Shams University · 1 drug in this class
- Daewoong Pharmaceutical Co. LTD. · 1 drug in this class
- Humanis Saglık Anonim Sirketi · 1 drug in this class
- Zhang Xiaofeng,MD · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Vonoprazan, Amoxicillin and Levofloxacin — Competitive Intelligence Brief. https://druglandscape.com/ci/vonoprazan-amoxicillin-and-levofloxacin. Accessed 2026-05-17.
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