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VIT-45 — Competitive Intelligence Brief
phase 3
Vitamin D analog
Vitamin D receptor (VDR)
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
VIT-45 (VIT-45) — American Regent, Inc.. VIT-45 is a vitamin D analog that enhances immune function and reduces inflammation through vitamin D receptor signaling.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| VIT-45 TARGET | VIT-45 | American Regent, Inc. | phase 3 | Vitamin D analog | Vitamin D receptor (VDR) | |
| Dovonex | CALCIPOTRIENE | marketed | Vitamin D Analog [EPC] | Vitamin D3 receptor | 1993-01-01 | |
| Alfarol 1.0 µg | Alfarol 1.0 µg | Eli Lilly and Company | marketed | Vitamin D analog | Vitamin D receptor (VDR) | |
| Hidroferol® | Hidroferol® | Hospital Universitario de Canarias | marketed | Vitamin D analog | Vitamin D receptor (VDR) | |
| Calcifediol Oral Product | Calcifediol Oral Product | OPKO Health, Inc. | marketed | Vitamin D analog | Vitamin D receptor (VDR) | |
| calcipotriene + clobetasol propionate | calcipotriene + clobetasol propionate | Leon Kircik, M.D. | marketed | Topical combination therapy (vitamin D analog + corticosteroid) | Vitamin D receptor (VDR) and glucocorticoid receptor (GR) | |
| Xamiol® Gel | Xamiol® Gel | LEO Pharma | marketed | Combination topical agent (vitamin D analog + corticosteroid) | Vitamin D receptor (VDR) and glucocorticoid receptor (GR) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Vitamin D analog class)
- LEO Pharma · 2 drugs in this class
- Genzyme, a Sanofi Company · 2 drugs in this class
- National Cancer Institute, Naples · 2 drugs in this class
- OPKO Health, Inc. · 2 drugs in this class
- Joslin Diabetes Center · 1 drug in this class
- Kyowa Kirin, Inc. · 1 drug in this class
- Maimónides Biomedical Research Institute of Córdoba · 1 drug in this class
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital · 1 drug in this class
- Shiraz University of Medical Sciences · 1 drug in this class
- St. Justine's Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). VIT-45 — Competitive Intelligence Brief. https://druglandscape.com/ci/vit-45. Accessed 2026-05-13.
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