Last reviewed · How we verify
Erivedge — Competitive Intelligence Brief
marketed
Hedgehog Pathway Inhibitor [EPC]
Smoothened
Oncology
Live · refreshed every 30 min
Target snapshot
Erivedge (vismodegib) — Roche. Vismodegib inhibits the Hedgehog pathway by binding to and blocking Smoothened, a key protein in the pathway.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Erivedge TARGET | vismodegib | Roche | marketed | Hedgehog Pathway Inhibitor [EPC] | Smoothened | 2012-01-01 |
| Daurismo | glasdegib | Pfizer | marketed | Hedgehog Pathway Inhibitor [EPC] | Smoothened homolog | 2018-01-01 |
| Daurismo | Glasdegib Maleate | Pfizer | marketed | Hedgehog pathway inhibitor | Smoothened (transmembrane protein) | 2018-01-01 |
| SONIDEGIB | SONIDEGIB | marketed | Smoothened | 2015-01-01 | ||
| Sonidegib Phosphate Capsules | Sonidegib Phosphate Capsules | Jemincare | marketed | Hedgehog pathway inhibitor | Smoothened (SMO) | |
| ERIVEDGE | ERIVEDGE | University Hospital, Lille | marketed | Hedgehog pathway inhibitor | Smoothened (SMO) | |
| Treatment with vismodegib | Treatment with vismodegib | University Hospital, Bordeaux | marketed | Hedgehog pathway inhibitor | Smoothened (SMO) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Hedgehog Pathway Inhibitor [EPC] class)
- · 1 drug in this class
- Pfizer · 1 drug in this class
- Roche · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- Erivedge CI watch — RSS
- Erivedge CI watch — Atom
- Erivedge CI watch — JSON
- Erivedge alone — RSS
- Whole Hedgehog Pathway Inhibitor [EPC] class — RSS
Cite this brief
Drug Landscape (2026). Erivedge — Competitive Intelligence Brief. https://druglandscape.com/ci/vismodegib. Accessed 2026-05-13.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab