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Erivedge — Competitive Intelligence Brief

Erivedge (vismodegib) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Hedgehog Pathway Inhibitor [EPC]. Area: Oncology.

marketed Hedgehog Pathway Inhibitor [EPC] Smoothened Oncology Live · refreshed every 30 min

Target snapshot

Erivedge (vismodegib) — Roche. Vismodegib inhibits the Hedgehog pathway by binding to and blocking Smoothened, a key protein in the pathway.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Erivedge TARGET vismodegib Roche marketed Hedgehog Pathway Inhibitor [EPC] Smoothened 2012-01-01
Daurismo glasdegib Pfizer marketed Hedgehog Pathway Inhibitor [EPC] Smoothened homolog 2018-01-01
Daurismo Glasdegib Maleate Pfizer marketed Hedgehog pathway inhibitor Smoothened (transmembrane protein) 2018-01-01
SONIDEGIB SONIDEGIB marketed Smoothened 2015-01-01
Sonidegib Phosphate Capsules Sonidegib Phosphate Capsules Jemincare marketed Hedgehog pathway inhibitor Smoothened (SMO)
ERIVEDGE ERIVEDGE University Hospital, Lille marketed Hedgehog pathway inhibitor Smoothened (SMO)
Treatment with vismodegib Treatment with vismodegib University Hospital, Bordeaux marketed Hedgehog pathway inhibitor Smoothened (SMO)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Hedgehog Pathway Inhibitor [EPC] class)

  1. · 1 drug in this class
  2. Pfizer · 1 drug in this class
  3. Roche · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Erivedge — Competitive Intelligence Brief. https://druglandscape.com/ci/vismodegib. Accessed 2026-05-13.

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