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Vehicle of ADX-102 Topical Dermal Cream — Competitive Intelligence Brief
phase 3
Complement inhibitor
Complement component 3 (C3)
Ophthalmology, Dermatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Vehicle of ADX-102 Topical Dermal Cream (Vehicle of ADX-102 Topical Dermal Cream) — Aldeyra Therapeutics, Inc.. ADX-102 is a topical dermal cream that targets the complement pathway to reduce inflammation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Vehicle of ADX-102 Topical Dermal Cream TARGET | Vehicle of ADX-102 Topical Dermal Cream | Aldeyra Therapeutics, Inc. | phase 3 | Complement inhibitor | Complement component 3 (C3) | |
| AVACINCAPTAD PEGOL SODIUM | AVACINCAPTAD PEGOL SODIUM | marketed | Complement Inhibitors | Complement C5 | 2023-01-01 | |
| Veopoz | POZELIMAB | Regeneron | marketed | Complement Inhibitor [EPC] | Complement C5 | 2023-01-01 |
| Ultomiris | RAVULIZUMAB | AstraZeneca | marketed | Complement Inhibitor [EPC] | Complement C5 | 2018-01-01 |
| H5G1.1 | ECULIZUMAB | AstraZeneca | marketed | Complement Inhibitor [EPC] | C5 | 2007-01-01 |
| C1 inhibitor (human) [C1 INH] | C1 inhibitor (human) [C1 INH] | Shire | marketed | Complement inhibitor / Serine protease inhibitor | C1s protease / Classical complement pathway | |
| Rucacuzumab plus standard therapy | Rucacuzumab plus standard therapy | Peking Union Medical College Hospital | marketed | Monoclonal antibody; complement inhibitor | C1q (complement component 1q) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — AVACINCAPTAD PEGOL SODIUM · 8236773 · Method of Use · US
- — AVACINCAPTAD PEGOL SODIUM · 9617546 · Compound · US
- — AVACINCAPTAD PEGOL SODIUM · 7579456 · Compound · US
- — AVACINCAPTAD PEGOL SODIUM · 11491176 · Method of Use · US
- — AVACINCAPTAD PEGOL SODIUM · 11273171 · Method of Use · US
- — AVACINCAPTAD PEGOL SODIUM · 12016875 · Method of Use · US
Sponsor landscape (Complement inhibitor class)
- CSL Behring · 3 drugs in this class
- Alexion Pharmaceuticals, Inc. · 2 drugs in this class
- Aldeyra Therapeutics, Inc. · 1 drug in this class
- BioCryst Pharmaceuticals · 1 drug in this class
- Haaglanden Medical Centre · 1 drug in this class
- InflaRx GmbH · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Vehicle of ADX-102 Topical Dermal Cream — Competitive Intelligence Brief. https://druglandscape.com/ci/vehicle-of-adx-102-topical-dermal-cream. Accessed 2026-05-17.
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