Who are VEGF Trap-Eye (BAY86-5321)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Aflibercept (Eylea), Aflibercept Intravitreous Injection, Intravitreal Aflibercept Injection, Eylea® (Aflibercept).

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Last reviewed 2026-05-18 · How we verify

VEGF Trap-Eye (BAY86-5321) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

VEGF Trap-Eye (BAY86-5321) (VEGF Trap-Eye (BAY86-5321)) competitive landscape: 4 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: VEGF inhibitor / Soluble decoy receptor. Area: Ophthalmology.

phase 3 VEGF inhibitor / Soluble decoy receptor VEGF (vascular endothelial growth factor) Ophthalmology Biologic Live · refreshed every 30 min

Target snapshot

VEGF Trap-Eye (BAY86-5321) (VEGF Trap-Eye (BAY86-5321)) — Bayer. VEGF Trap-Eye is a soluble decoy receptor that binds and neutralizes vascular endothelial growth factor (VEGF) to inhibit abnormal blood vessel growth in the eye.

Comparator set (4 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
VEGF Trap-Eye (BAY86-5321) TARGET	VEGF Trap-Eye (BAY86-5321)	Bayer	phase 3	VEGF inhibitor / Soluble decoy receptor	VEGF (vascular endothelial growth factor)
Aflibercept (Eylea)	Aflibercept (Eylea)	Ahmad Zeeshan Jamil	marketed	VEGF inhibitor / Soluble decoy receptor	VEGF-A, VEGF-B, PlGF (Placental Growth Factor)
Aflibercept Intravitreous Injection	Aflibercept Intravitreous Injection	Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine	marketed	VEGF inhibitor / Soluble decoy receptor	VEGF-A, VEGF-B, PlGF (placental growth factor)
Intravitreal Aflibercept Injection	Intravitreal Aflibercept Injection	Ophthalmic Consultants of Boston	marketed	VEGF inhibitor / Soluble decoy receptor	VEGF-A, VEGF-B, PlGF (Placental Growth Factor)
Eylea® (Aflibercept)	Eylea® (Aflibercept)	Alvotech Swiss AG	phase 3	VEGF inhibitor / Soluble decoy receptor	VEGF-A, VEGF-B, PlGF (Placental Growth Factor)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (VEGF inhibitor / Soluble decoy receptor class)

Ahmad Zeeshan Jamil · 1 drug in this class
Alvotech Swiss AG · 1 drug in this class
Bayer · 1 drug in this class
Ophthalmic Consultants of Boston · 1 drug in this class
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine · 1 drug in this class

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Cite this brief

Drug Landscape (2026). VEGF Trap-Eye (BAY86-5321) — Competitive Intelligence Brief. https://druglandscape.com/ci/vegf-trap-eye-bay86-5321. Accessed 2026-05-18.

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