Who are VALACYCLOVIR's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Acyclovir (ACV), Valacyclovir (ZELITREX), Masked Oral Valacyclovir, intravenous (IV) ganciclovir, Generic acyclovir, ACYC vehicle.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

VALACYCLOVIR — Competitive Intelligence Brief

VALACYCLOVIR (VALACYCLOVIR) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Nucleoside analogue. Area: Metabolic.

marketed Nucleoside analogue Viral DNA polymerase Metabolic Small molecule Live · refreshed every 30 min

Target snapshot

VALACYCLOVIR (VALACYCLOVIR). Valacyclovir is an antiviral drug that inhibits viral DNA polymerase to treat herpes simplex and varicella-zoster viruses.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
VALACYCLOVIR TARGET	VALACYCLOVIR		marketed	Nucleoside analogue	Viral DNA polymerase	1995-01-01
Acyclovir (ACV)	Acyclovir (ACV)	French National Agency for Research on AIDS and Viral Hepatitis	marketed	Nucleoside analog antiviral	Viral DNA polymerase (herpes simplex virus and varicella-zoster virus)
Valacyclovir (ZELITREX)	Valacyclovir (ZELITREX)	Assistance Publique - Hôpitaux de Paris	marketed	Nucleoside analog antiviral	Viral DNA polymerase (herpesvirus)
Masked Oral Valacyclovir	Masked Oral Valacyclovir	NYU Langone Health	marketed	Nucleoside analog antiviral	Viral DNA polymerase (HSV and VZV)
intravenous (IV) ganciclovir	intravenous (IV) ganciclovir	University of Oslo School of Pharmacy	marketed	Nucleoside analog antiviral	Viral DNA polymerase (CMV and herpes simplex virus)
Generic acyclovir	Generic acyclovir	University of Washington	phase 3	Nucleoside analog antiviral	Viral DNA polymerase (HSV and VZV)
ACYC vehicle	ACYC vehicle	Bausch Health Americas, Inc.	phase 3	Antiviral agent (topical formulation)	Viral DNA polymerase (via acyclovir active ingredient)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Nucleoside analogue class)

· 1 drug in this class
Hospital Universitari Vall d'Hebron Research Institute · 1 drug in this class

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Cite this brief

Drug Landscape (2026). VALACYCLOVIR — Competitive Intelligence Brief. https://druglandscape.com/ci/valacyclovir. Accessed 2026-05-13.

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