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TS-172 — Competitive Intelligence Brief
phase 3
Serotonin receptor antagonist
5-HT2A receptor
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
TS-172 (TS-172) — Taisho Pharmaceutical Co., Ltd.. TS-172 is a small molecule that targets the serotonin receptor.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| TS-172 TARGET | TS-172 | Taisho Pharmaceutical Co., Ltd. | phase 3 | Serotonin receptor antagonist | 5-HT2A receptor | |
| Risperidone and Ramelteon | Risperidone and Ramelteon | All India Institute of Medical Sciences, Bhubaneswar | marketed | Atypical antipsychotic + melatonin receptor agonist combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, melatonin MT1/MT2 receptors | |
| Risperdal,reminyl | Risperdal,reminyl | Jinan Mental Hospital | marketed | Atypical antipsychotic (Risperdal); Cholinesterase inhibitor (Reminyl) | Dopamine D2 receptor, serotonin 5-HT2A receptor (Risperdal); Acetylcholinesterase (Reminyl) | |
| Quetiapine or Risperidone + Aripiprazole | Quetiapine or Risperidone + Aripiprazole | Otsuka Pharmaceutical Development & Commercialization, Inc. | marketed | Atypical antipsychotic | Dopamine D2 receptor, serotonin 5-HT2A receptor | |
| risperidone (Risperdal) | risperidone (Risperdal) | University of South Florida | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| sodium valproate with Clozapine | sodium valproate with Clozapine | Shanghai Mental Health Center | marketed | Antipsychotic + mood stabilizer combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, GABA pathways, histone deacetylase | |
| Perospirone hydrochloride tablets | Perospirone hydrochloride tablets | Shanghai Mental Health Center | marketed | Atypical antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Serotonin receptor antagonist class)
- Addpharma Inc. · 2 drugs in this class
- Shire · 2 drugs in this class
- Gedeon Richter Plc. · 1 drug in this class
- Geropharm · 1 drug in this class
- H. Lundbeck A/S · 1 drug in this class
- Infan Industria Quimica Farmaceutica Nacional · 1 drug in this class
- Phytopharm Consulting Brazil · 1 drug in this class
- Taisho Pharmaceutical Co., Ltd. · 1 drug in this class
- Aclaris Therapeutics, Inc. · 1 drug in this class
- Visirna Therapeutics HK Limited · 1 drug in this class
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Cite this brief
Drug Landscape (2026). TS-172 — Competitive Intelligence Brief. https://druglandscape.com/ci/ts-172. Accessed 2026-05-14.
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