Who are Topotecan (Chemotherapy)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Camptosar, Idamycin Pfs, Idamycin Pfs, Idamycin Pfs, Cipro, Amekrin.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-17 · How we verify

Topotecan (Chemotherapy) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Topotecan (Chemotherapy) (Topotecan (Chemotherapy)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Topoisomerase inhibitor. Area: Oncology.

phase 3 Topoisomerase inhibitor Topoisomerase I Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Topotecan (Chemotherapy) (Topotecan (Chemotherapy)) — Hoffmann-La Roche. Topotecan is a topoisomerase I inhibitor that works by interfering with the enzyme topoisomerase I, which is involved in DNA replication and repair.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Topotecan (Chemotherapy) TARGET	Topotecan (Chemotherapy)	Hoffmann-La Roche	phase 3	Topoisomerase inhibitor	Topoisomerase I
Camptosar	irinotecan	Pfizer	marketed	Topoisomerase Inhibitor	topoisomerase I	1996-01-01
Idamycin Pfs	Idarubicin Hydrochloride	Pfizer Inc.	marketed	Anthracycline topoisomerase inhibitor	DNA, Topoisomerase II	1990-01-01
Idamycin Pfs	IDARUBICIN HYDROCHLORIDE		marketed	Anthracycline Topoisomerase Inhibitor	DNA, topoisomerase II	1990-01-01
Idamycin Pfs	Idarubicin Hydrochloride	Pfizer Inc.	marketed	Anthracycline topoisomerase inhibitor	DNA, Topoisomerase II	1990-01-01
Cipro	ciprofloxacin	Bayer AG	marketed	Fluoroquinolone antibiotic	DNA topoisomerase II, DNA gyrase subunit A, DNA gyrase subunit A	1987-10-22
Amekrin	AMSACRINE		marketed	amsacrine	DNA topoisomerase 2-beta, Solute carrier family 22 member 1, DNA topoisomerase II	1987-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2029-04-21 — Cipro · 11369566 · Formulation · US
2029-04-21 — Cipro · 9603796 · Compound · US
2029-04-21 — Cipro · 9205048 · Method of Use · US
2029-12-11 — Cipro · 9233068 · Formulation · US
2030-04-27 — Cipro · 8318817 · Method of Use · US
2035-07-01 — Cipro · 9220796 · Formulation · US
2037-11-12 — Cipro · 11040004 · Method of Use · US
2038-11-27 — Cipro · 11246863 · Formulation · US

Sponsor landscape (Topoisomerase inhibitor class)

Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator, IRB Chair · 1 drug in this class
Hoffmann-La Roche · 1 drug in this class
Sun Yat-sen University · 1 drug in this class
Taiho Pharmaceutical Co., Ltd. · 1 drug in this class
Unity Health Toronto · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Topotecan (Chemotherapy) — Competitive Intelligence Brief. https://druglandscape.com/ci/topotecan-chemotherapy. Accessed 2026-05-17.

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