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Topiramate-Implant — Competitive Intelligence Brief
marketed
Anticonvulsant / Antiepileptic agent
GABA-A receptor, sodium channels, glutamate receptors
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Topiramate-Implant (Topiramate-Implant) — University of Sao Paulo. Topiramate is a sulfamate-substituted monosaccharide that enhances GABA-mediated inhibition and blocks sodium channels to reduce neuronal excitability.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Topiramate-Implant TARGET | Topiramate-Implant | University of Sao Paulo | marketed | Anticonvulsant / Antiepileptic agent | GABA-A receptor, sodium channels, glutamate receptors | |
| Topiramate monotherapy | Topiramate monotherapy | Johnson & Johnson Taiwan Ltd | marketed | Anticonvulsant / Antiepileptic agent | GABA-A receptor; voltage-gated sodium channels | |
| zonisamide low dose group | zonisamide low dose group | Eisai Korea Inc. | marketed | Anticonvulsant / Antiepileptic agent | Sodium channels, calcium channels, carbonic anhydrase | |
| Standard dose topiramate | Standard dose topiramate | Mario Negri Institute for Pharmacological Research | marketed | Anticonvulsant / Antiepileptic agent | Voltage-gated sodium channels, GABA-A receptors, carbonic anhydrase | |
| Topiramate Standard | Topiramate Standard | Janssen Korea, Ltd., Korea | marketed | Anticonvulsant / Antiepileptic agent | Voltage-gated sodium channels, GABA-A receptors, carbonic anhydrase | |
| Carbamazepine-Implant | Carbamazepine-Implant | University of Sao Paulo | marketed | Anticonvulsant / Antiepileptic agent | Voltage-gated sodium channels | |
| carbamazepine oxcarbazepine | carbamazepine oxcarbazepine | Odense University Hospital | marketed | Anticonvulsant / Antiepileptic agent | Voltage-gated sodium channels |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Anticonvulsant / Antiepileptic agent class)
- University of Sao Paulo · 2 drugs in this class
- Mario Negri Institute for Pharmacological Research · 2 drugs in this class
- Janssen Korea, Ltd., Korea · 1 drug in this class
- Johnson & Johnson Taiwan Ltd · 1 drug in this class
- Ministry of Health and Sports, Myanmar · 1 drug in this class
- Odense University Hospital · 1 drug in this class
- UCB BIOSCIENCES GmbH · 1 drug in this class
- University Hospitals Cleveland Medical Center · 1 drug in this class
- Eisai Korea Inc. · 1 drug in this class
- Upsher-Smith Laboratories · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Topiramate-Implant — Competitive Intelligence Brief. https://druglandscape.com/ci/topiramate-implant. Accessed 2026-05-16.
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