Who are Topical Adapalene Gel 0.1%'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Sohonos, TRIFAROTENE, Panretin, Targretin, Differin, Soriatane.

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Last reviewed 2026-05-17 · How we verify

Topical Adapalene Gel 0.1% — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Topical Adapalene Gel 0.1% (Topical Adapalene Gel 0.1%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Retinoid. Area: Dermatology.

marketed Retinoid Retinoic acid receptor gamma (RARγ) Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

Topical Adapalene Gel 0.1% (Topical Adapalene Gel 0.1%) — University of Louisville. Adapalene is a third-generation retinoid that binds to retinoic acid receptors to normalize skin cell differentiation and reduce inflammation in acne.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Topical Adapalene Gel 0.1% TARGET	Topical Adapalene Gel 0.1%	University of Louisville	marketed	Retinoid	Retinoic acid receptor gamma (RARγ)
Sohonos	PALOVAROTENE	Ipsen	marketed	Retinoid [EPC]	Retinoic acid receptor gamma	2023-01-01
TRIFAROTENE	TRIFAROTENE		marketed	Retinoid [EPC]		2019-01-01
Panretin	ALITRETINOIN	Advanz	marketed	Retinoid [EPC]	Retinoic acid receptor beta	1999-01-01
Targretin	BEXAROTENE	Bausch Health	marketed	Retinoid [EPC]	Retinoic acid receptor RXR-beta	1999-01-01
Differin	ADAPALENE	Galderma Labs Lp	marketed	Retinoid [EPC]	Retinoic acid receptor beta	1996-01-01
Soriatane	ACITRETIN	Stiefel Labs Inc	marketed	Retinoid [EPC]	Bile salt export pump	1996-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2026-09-15 — Differin · 8435502 · Formulation · US
2026-09-15 — Differin · 8709392 · Formulation · US
2028-05-31 — Differin · 7998467 · Formulation · US

Sponsor landscape (Retinoid class)

Galderma R&D · 8 drugs in this class
Bausch Health Americas, Inc. · 4 drugs in this class
Stiefel, a GSK Company · 2 drugs in this class
Army Medical University, China · 1 drug in this class
Centro Dermatológico Dr. Ladislao de la Pascua · 1 drug in this class
Cipher Pharmaceuticals Inc. · 1 drug in this class
Center for Sight Las Vegas · 1 drug in this class
Dr. Reddy's Laboratories Limited · 1 drug in this class
Dr.dr.Irma Bernadette, SpKK (K) · 1 drug in this class
Dr. Emmy Graber · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Topical Adapalene Gel 0.1% — Competitive Intelligence Brief. https://druglandscape.com/ci/topical-adapalene-gel-0-1. Accessed 2026-05-17.

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