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tenofovir, lamivudine, efavirenz — Competitive Intelligence Brief
marketed
Antiretroviral combination therapy (NRTI/NtRTI/NNRTI)
HIV reverse transcriptase, HIV integrase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
tenofovir, lamivudine, efavirenz (tenofovir, lamivudine, efavirenz) — Bamrasnaradura Infectious Diseases Institute. This is a fixed-dose combination of three antiretroviral drugs that inhibit HIV reverse transcriptase and integrase to suppress viral replication.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| tenofovir, lamivudine, efavirenz TARGET | tenofovir, lamivudine, efavirenz | Bamrasnaradura Infectious Diseases Institute | marketed | Antiretroviral combination therapy (NRTI/NtRTI/NNRTI) | HIV reverse transcriptase, HIV integrase | |
| TDF/3TC/EFV or DTG or NVP | TDF/3TC/EFV or DTG or NVP | MU-JHU CARE | marketed | Antiretroviral combination therapy (NRTI + NNRTI or INSTI) | HIV reverse transcriptase, HIV integrase | |
| Switch to Triumeq | Switch to Triumeq | McGill University Health Centre/Research Institute of the McGill University Health Centre | marketed | Antiretroviral combination therapy (NRTI + INSTI) | HIV reverse transcriptase, HIV integrase | |
| efavirenz + emtricitabina + tenofovir | efavirenz + emtricitabina + tenofovir | Hospital Universitari Vall d'Hebron Research Institute | marketed | Antiretroviral combination therapy (NNRTI + NRTI + NtRTI) | HIV reverse transcriptase, HIV integrase | |
| Doravirine, Tenofovir, Lamivudine | Doravirine, Tenofovir, Lamivudine | Merck Sharp & Dohme LLC | marketed | Antiretroviral combination (NNRTI + NRTIs) | HIV reverse transcriptase, HIV integrase | |
| Atripla or Stribild | Atripla or Stribild | Fred Hutchinson Cancer Center | marketed | Antiretroviral combination therapy (NRTI/NNRTI or INSTI-based) | HIV reverse transcriptase, HIV integrase | |
| DOR/DTG/3TC | DOR/DTG/3TC | Insel Gruppe AG, University Hospital Bern | marketed | Antiretroviral combination (NNRTI + INSTI + NRTI) | HIV reverse transcriptase, HIV integrase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination therapy (NRTI/NtRTI/NNRTI) class)
- Bamrasnaradura Infectious Diseases Institute · 1 drug in this class
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Cite this brief
Drug Landscape (2026). tenofovir, lamivudine, efavirenz — Competitive Intelligence Brief. https://druglandscape.com/ci/tenofovir-lamivudine-efavirenz. Accessed 2026-05-17.
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