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Tnkase — Competitive Intelligence Brief
marketed
fibrin
Immunology
Enzyme
Live · refreshed every 30 min
Target snapshot
Tnkase (TENECTEPLASE) — Roche. Tenecteplase binds to fibrin and converts plasminogen to plasmin, enhancing fibrin-specific plasmin generation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Tnkase TARGET | TENECTEPLASE | Roche | marketed | fibrin | 2000-01-01 | |
| low-dose tenecteplase intravenous thrombolysis | low-dose tenecteplase intravenous thrombolysis | Southwest Hospital, China | marketed | Fibrinolytic agent / Tissue plasminogen activator (tPA) | Plasminogen / Fibrin | |
| RiaSTAP | RiaSTAP | Weill Medical College of Cornell University | marketed | Fibrinogen concentrate | Fibrinogen (Factor I) | |
| EVARREST™ | EVARREST™ | Ethicon, Inc. | marketed | Topical hemostatic agent | Fibrinogen (Factor I) and thrombin (Factor IIa) | |
| Trypsin-Chymotrypsin | Trypsin-Chymotrypsin | Dow University of Health Sciences | marketed | Proteolytic enzyme combination | Protein substrates and fibrin | |
| Tenecteplase thrombolysis | Tenecteplase thrombolysis | Xuanwu Hospital, Beijing | marketed | Fibrinolytic agent / Thrombolytic | Fibrin; Plasminogen | |
| Traditional Cryoprecipitate | Traditional Cryoprecipitate | Weill Medical College of Cornell University | marketed | Blood product; clotting factor concentrate | Fibrinogen, Factor VIII, von Willebrand factor, Fibronectin, Factor XIII |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape
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Cite this brief
Drug Landscape (2026). Tnkase — Competitive Intelligence Brief. https://druglandscape.com/ci/tenecteplase. Accessed 2026-05-13.
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