Who are Tegafur-uracil (UFT)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Xeloda, Fudr, Folic Acid, Metafolin, 5-fluoro-uracil, Folferi and celecoxib.

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Last reviewed 2026-06-10 · How we verify

Tegafur-uracil (UFT) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Tegafur-uracil (UFT) (Tegafur-uracil (UFT)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimetabolite. Area: Oncology.

phase 3 Antimetabolite Thymidylate synthase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Tegafur-uracil (UFT) (Tegafur-uracil (UFT)) — Multicenter Clinical Study Group of Osaka, Colorectal Cancer Treatment Group. Tegafur-uracil (UFT) is a prodrug that is metabolized into 5-fluorouracil (5-FU), which then inhibits thymidylate synthase.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Tegafur-uracil (UFT) TARGET	Tegafur-uracil (UFT)	Multicenter Clinical Study Group of Osaka, Colorectal Cancer Treatment Group	phase 3	Antimetabolite	Thymidylate synthase
Xeloda	capecitabine	Cheplapharm	marketed	Nucleoside Metabolic Inhibitor [EPC]	Thymidylate synthase	1998-01-01
Fudr	FLOXURIDINE		marketed	Antimetabolite [EPC]	Thymidylate synthase	1970-01-01
Folic Acid	FOLIC ACID	Pfizer	marketed	Vitamin C [EPC]	Thymidylate synthase	1946-01-01
Metafolin	Metafolin	University of California, San Diego	marketed		Thymidylate synthase
5-fluoro-uracil	5-fluoro-uracil	UNICANCER	marketed	Antimetabolite	Thymidylate synthase; RNA and DNA incorporation
Folferi and celecoxib	Folferi and celecoxib	Sherief Abd-Elsalam	marketed	Chemotherapy combination with COX-2 inhibitor	Topoisomerase I (irinotecan), thymidylate synthase (fluorouracil), COX-2

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimetabolite class)

Grupo Espanol Multidisciplinario del Cancer Digestivo · 2 drugs in this class
NRG Oncology · 2 drugs in this class
Bristol-Myers Squibb · 1 drug in this class
EMD Serono Research & Development Institute, Inc. · 1 drug in this class
GERCOR - Multidisciplinary Oncology Cooperative Group · 1 drug in this class
Hoffmann-La Roche · 1 drug in this class
Centre Oscar Lambret · 1 drug in this class
Iwate Medical University · 1 drug in this class
Janssen Research & Development, LLC · 1 drug in this class
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Tegafur-uracil (UFT) — Competitive Intelligence Brief. https://druglandscape.com/ci/tegafur-uracil-uft. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing