Last reviewed · How we verify
Metafolin
At a glance
| Generic name | Metafolin |
|---|---|
| Sponsor | University of California, San Diego |
| Target | Thymidylate synthase |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | FDA-approved |
Approved indications
- Acne vulgaris
- Contraception
- Premenstrual dysphoric disorder
Common side effects
- Allergic sensitization
- Fatigue
Key clinical trials
- Pharmacokinetic Study of Eicosapentaenoic Acid (EPA) and Calcium L-5-Methyltetrahydrofolate (L-5-MTHF) After Administration of CreNeuroS® CNS Fish Oil Plus Softgels in Healthy Subjects Under Fasting Conditions (NA)
- Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian Syndrome (PHASE3)
- Prenatal Iodine Supplementation and Early Childhood Neurodevelopment (PHASE4)
- Impact of High-dose Folic Acid Supplementation on Pathways Linked to DNA Formation (NA)
- Natural Folate vs. Synthetic Folic Acid in Pregnancy (NA)
- INAS-FOCUS (International Active Surveillance Study - Folate in Oral Contraceptives Utilization Study)
- Low Dose OC Therapy in Women With Polycystic Ovary Syndrome (PCOS): Impact of BMI on Hyperandrogenism (PHASE4)
- Bioequivalence Study: 2 mg Estradiol Valerate (EV) and 3 mg Dienogest (DNG) Without and With Levomefolate Calcium (PHASE1)
Primary sources
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| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |