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tegafur-uracil — Competitive Intelligence Brief

tegafur-uracil (tegafur-uracil) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimetabolite; 5-fluorouracil prodrug. Area: Oncology.

marketed Antimetabolite; 5-fluorouracil prodrug Thymidylate synthase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

tegafur-uracil (tegafur-uracil) — Yokohama City University. Tegafur-uracil is a combination prodrug that is converted to fluorouracil in the body to inhibit thymidylate synthase and disrupt DNA synthesis in cancer cells.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
tegafur-uracil TARGET tegafur-uracil Yokohama City University marketed Antimetabolite; 5-fluorouracil prodrug Thymidylate synthase
Xeloda capecitabine Cheplapharm marketed Nucleoside Metabolic Inhibitor [EPC] Thymidylate synthase 1998-01-01
Fudr FLOXURIDINE marketed Antimetabolite [EPC] Thymidylate synthase 1970-01-01
Folic Acid FOLIC ACID Pfizer marketed Vitamin C [EPC] Thymidylate synthase 1946-01-01
Fluorouracil Injection Fluorouracil Injection Suzhou Suncadia Biopharmaceuticals Co., Ltd. marketed Antimetabolite Thymidylate synthase
5-Fluorouracile 5-Fluorouracile Groupe Oncologie Radiotherapie Tete et Cou marketed Antimetabolite; pyrimidine analog Thymidylate synthase; RNA and DNA incorporation
5-Fluouracil 5-Fluouracil Hoffmann-La Roche marketed Antimetabolite Thymidylate synthase; RNA and DNA incorporation

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimetabolite; 5-fluorouracil prodrug class)

  1. Liaoning Cancer Hospital & Institute · 1 drug in this class
  2. Yokohama City University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). tegafur-uracil — Competitive Intelligence Brief. https://druglandscape.com/ci/tegafur-uracil. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing