Who are Zosyn's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Xacduro (Copackaged), Vabomere, Avycaz, Unasyn, Augmentin 250.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Zosyn — Competitive Intelligence Brief

Zosyn (TAZOBACTAM) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: beta Lactamase Inhibitor. Area: Metabolic.

marketed beta Lactamase Inhibitor Metabolic Small molecule Live · refreshed every 30 min

Target snapshot

Zosyn (TAZOBACTAM) — Merck Sharp & Dohme B.V.. Zosyn works by blocking bacterial enzymes that break down antibiotics, allowing the antibiotics to kill bacteria more effectively.

Comparator set (5 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Zosyn TARGET	TAZOBACTAM	Merck Sharp & Dohme B.V.	marketed	beta Lactamase Inhibitor		1993-01-01
Xacduro (Copackaged)	DURLOBACTAM	Entasis Therap	marketed	beta Lactamase Inhibitor		2023-01-01
Vabomere	VABORBACTAM	Rempex Pharms Inc	marketed	beta Lactamase Inhibitor [EPC]		2017-01-01
Avycaz	AVIBACTAM	Cerexa Inc	marketed	beta Lactamase Inhibitor [EPC]		2015-01-01
Unasyn	SULBACTAM	Pfizer	marketed	beta Lactamase Inhibitor	Serine beta-lactamase-like protein LACTB, mitochondrial	1986-01-01
Augmentin 250	CLAVULANIC ACID	Dr Reddys Labs Inc	marketed	beta Lactamase Inhibitor		1984-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2026-11-12 — Avycaz · 7612087 · US
2028-05-15 — Zosyn · 7129232 · US
2030-10-08 — Avycaz · 8835455 · US
2031-08-08 — Vabomere · 11007206 · US
2031-08-08 — Vabomere · 10172874 · US
2031-08-08 — Vabomere · 10183034 · US
2031-08-08 — Vabomere · 10561675 · US
2031-08-08 — Vabomere · 9694025 · US
2031-08-12 — Avycaz · 8471025 · US
2031-08-29 — Vabomere · 8680136 · US
2032-06-15 — Avycaz · 9695122 · US
2032-06-15 — Avycaz · 8969566 · US
2032-06-15 — Avycaz · 9284314 · US
2032-09-07 — Zosyn · 10028963 · US
2032-09-07 — Zosyn · 9724353 · US
2032-09-27 — Zosyn · 8685957 · US
2032-09-27 — Zosyn · 8476425 · US
2033-04-02 — Xacduro (Copackaged) · 9309245 · US
2033-04-02 — Unasyn · 9309245 · US
2033-04-02 — Xacduro (Copackaged) · 9623014 · US
2033-04-02 — Unasyn · 9623014 · US
2034-03-14 — Zosyn · 8968753 · US
2034-03-14 — Zosyn · 10420841 · US
2034-03-14 — Zosyn · 11278622 · US
2034-03-14 — Zosyn · 9872906 · US
2034-03-14 — Zosyn · 9320740 · US
2034-05-28 — Zosyn · 8906898 · US
2034-09-09 — Zosyn · 10376496 · US
2034-09-09 — Zosyn · 10933053 · US
2035-08-14 — Zosyn · 10125149 · US

Sponsor landscape (beta Lactamase Inhibitor class)

Dr Reddys Labs Inc · 1 drug in this class
Entasis Therap · 1 drug in this class
Merck Sharp & Dohme B.V. · 1 drug in this class
Pfizer · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Zosyn — Competitive Intelligence Brief. https://druglandscape.com/ci/tazobactam. Accessed 2026-05-14.

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