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TAS-118 plus Oxaliplatin — Competitive Intelligence Brief
phase 3
Thymidylate synthase inhibitor
Thymidylate synthase
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
TAS-118 plus Oxaliplatin (TAS-118 plus Oxaliplatin) — Taiho Pharmaceutical Co., Ltd.. TAS-118 is a thymidylate synthase inhibitor, and when combined with oxaliplatin, it targets rapidly dividing cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| TAS-118 plus Oxaliplatin TARGET | TAS-118 plus Oxaliplatin | Taiho Pharmaceutical Co., Ltd. | phase 3 | Thymidylate synthase inhibitor | Thymidylate synthase | |
| Xeloda | capecitabine | Cheplapharm | marketed | Nucleoside Metabolic Inhibitor [EPC] | Thymidylate synthase | 1998-01-01 |
| Fudr | FLOXURIDINE | marketed | Antimetabolite [EPC] | Thymidylate synthase | 1970-01-01 | |
| Folic Acid | FOLIC ACID | Pfizer | marketed | Vitamin C [EPC] | Thymidylate synthase | 1946-01-01 |
| Xeloda | Xeloda | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | marketed | Thymidylate synthase | ||
| Irinotecan, 5FU, leucovorin | Irinotecan, 5FU, leucovorin | Asan Medical Center | marketed | Chemotherapy combination (topoisomerase I inhibitor + antimetabolite) | Topoisomerase I; thymidylate synthase | |
| Oxaliplatin;Capecitabine | Oxaliplatin;Capecitabine | Hebei Medical University | marketed | Platinum-based chemotherapy combination; antimetabolite | DNA (oxaliplatin); thymidylate synthase (capecitabine/5-FU) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Thymidylate synthase inhibitor class)
- Taiho Pharmaceutical Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). TAS-118 plus Oxaliplatin — Competitive Intelligence Brief. https://druglandscape.com/ci/tas-118-plus-oxaliplatin. Accessed 2026-05-16.
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