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SYD-101 0.03% — Competitive Intelligence Brief

SYD-101 0.03% (SYD-101 0.03%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antifungal agent. Area: Dermatology/Infectious Disease.

phase 3 Antifungal agent Dermatology/Infectious Disease Small molecule Live · refreshed every 30 min

Target snapshot

SYD-101 0.03% (SYD-101 0.03%) — Sydnexis, Inc.. SYD-101 is a topical antifungal agent that disrupts fungal cell membrane integrity.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
SYD-101 0.03% TARGET SYD-101 0.03% Sydnexis, Inc. phase 3 Antifungal agent
Ciclopirox NL Ciclopirox NL Galderma R&D marketed Topical antifungal agent Fungal cytochrome P450 enzymes (via metal ion chelation)
Antifungal treatment Antifungal treatment Hospices Civils de Lyon marketed Antifungal agent (class varies by specific drug: azole, polyene, echinocandin, or other)
Ciclopirox 8% Ciclopirox 8% MIP Brasil Indústria e Comércio de Produtos Farmacêuticos LTDA marketed Topical antifungal agent Fungal cytochrome P450 enzymes and polyvalent cation-dependent metalloenzymes
Topical Antimicrobial/Antifungal Medications Topical Antimicrobial/Antifungal Medications Mylan Inc. marketed Topical antimicrobial/antifungal agents (multiple classes)
Ticlopidine and itraconazole Ticlopidine and itraconazole Turku University Hospital marketed Antiplatelet agent + Antifungal agent ADP receptor (P2Y12) for ticlopidine; Fungal CYP51 for itraconazole
POLYGYNAX® POLYGYNAX® Laboratoire Innotech International phase 3 Combination antibiotic and antifungal agent

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antifungal agent class)

  1. Moberg Pharma AB · 1 drug in this class
  2. Padagis LLC · 1 drug in this class
  3. Sydnexis, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). SYD-101 0.03% — Competitive Intelligence Brief. https://druglandscape.com/ci/syd-101-0-03. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing