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SYD-101 0.03% — Competitive Intelligence Brief
phase 3
Antifungal agent
Dermatology/Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
SYD-101 0.03% (SYD-101 0.03%) — Sydnexis, Inc.. SYD-101 is a topical antifungal agent that disrupts fungal cell membrane integrity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| SYD-101 0.03% TARGET | SYD-101 0.03% | Sydnexis, Inc. | phase 3 | Antifungal agent | ||
| Ciclopirox NL | Ciclopirox NL | Galderma R&D | marketed | Topical antifungal agent | Fungal cytochrome P450 enzymes (via metal ion chelation) | |
| Antifungal treatment | Antifungal treatment | Hospices Civils de Lyon | marketed | Antifungal agent (class varies by specific drug: azole, polyene, echinocandin, or other) | ||
| Ciclopirox 8% | Ciclopirox 8% | MIP Brasil Indústria e Comércio de Produtos Farmacêuticos LTDA | marketed | Topical antifungal agent | Fungal cytochrome P450 enzymes and polyvalent cation-dependent metalloenzymes | |
| Topical Antimicrobial/Antifungal Medications | Topical Antimicrobial/Antifungal Medications | Mylan Inc. | marketed | Topical antimicrobial/antifungal agents (multiple classes) | ||
| Ticlopidine and itraconazole | Ticlopidine and itraconazole | Turku University Hospital | marketed | Antiplatelet agent + Antifungal agent | ADP receptor (P2Y12) for ticlopidine; Fungal CYP51 for itraconazole | |
| POLYGYNAX® | POLYGYNAX® | Laboratoire Innotech International | phase 3 | Combination antibiotic and antifungal agent |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antifungal agent class)
- Moberg Pharma AB · 1 drug in this class
- Padagis LLC · 1 drug in this class
- Sydnexis, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). SYD-101 0.03% — Competitive Intelligence Brief. https://druglandscape.com/ci/syd-101-0-03. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing