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Switch from tenofovir to abacavir — Competitive Intelligence Brief
phase 3
NRTI
Reverse transcriptase
Infectious Diseases
Small molecule
Live · refreshed every 30 min
Target snapshot
Switch from tenofovir to abacavir (Switch from tenofovir to abacavir) — Germans Trias i Pujol Hospital. Abacavir is a nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the replication of HIV.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Switch from tenofovir to abacavir TARGET | Switch from tenofovir to abacavir | Germans Trias i Pujol Hospital | phase 3 | NRTI | Reverse transcriptase | |
| Twice-daily ABC+3TC | Twice-daily ABC+3TC | Medical Research Council | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) combination | HIV reverse transcriptase | |
| Tenofovir/Emtricitabine | Tenofovir/Emtricitabine | Bristol-Myers Squibb | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor (NRTI/NtRTI) combination | HIV reverse transcriptase | |
| Entecavir+Fuzheng Huayu+TCM Granule | Entecavir+Fuzheng Huayu+TCM Granule | ShuGuang Hospital | marketed | Nucleoside reverse transcriptase inhibitor + Traditional Chinese Medicine herbal combination | HBV reverse transcriptase (entecavir component); multiple herbal constituents with unclear specific molecular targets | |
| Symtuza® (TAF/FTC/DRV/c) | Symtuza® (TAF/FTC/DRV/c) | Fundacion SEIMC-GESIDA | marketed | Antiretroviral combination (NRTI/INSTI class with protease inhibitor) | HIV reverse transcriptase, HIV protease, CYP3A4 | |
| AZT | AZT | Johns Hopkins Bloomberg School of Public Health | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase | |
| "Raltegravir" and "Zidovudine" | "Raltegravir" and "Zidovudine" | Universidad Peruana Cayetano Heredia | marketed | Antiretroviral combination (integrase inhibitor + nucleoside reverse transcriptase inhibitor) | HIV integrase (raltegravir); HIV reverse transcriptase (zidovudine) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (NRTI class)
- Germans Trias i Pujol Hospital · 1 drug in this class
- Merck Sharp & Dohme LLC · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Switch from tenofovir to abacavir — Competitive Intelligence Brief. https://druglandscape.com/ci/switch-from-tenofovir-to-abacavir. Accessed 2026-05-16.
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