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Sulfamethoxazole-Trimethoprim — Competitive Intelligence Brief

Sulfamethoxazole-Trimethoprim (Sulfamethoxazole-Trimethoprim) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Sulfonamide-dihydrofolate reductase inhibitor combination. Area: Infectious Disease.

marketed Sulfonamide-dihydrofolate reductase inhibitor combination Dihydropteroate synthase; Dihydrofolate reductase Infectious Disease Small molecule Live · refreshed every 30 min

Target snapshot

Sulfamethoxazole-Trimethoprim (Sulfamethoxazole-Trimethoprim) — National Institute of Allergy and Infectious Diseases (NIAID). Sulfamethoxazole-trimethoprim is a fixed-dose combination antibiotic that inhibits bacterial folate synthesis by blocking dihydrofolate reductase and dihydropteroate synthase.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Sulfamethoxazole-Trimethoprim TARGET Sulfamethoxazole-Trimethoprim National Institute of Allergy and Infectious Diseases (NIAID) marketed Sulfonamide-dihydrofolate reductase inhibitor combination Dihydropteroate synthase; Dihydrofolate reductase
Sulfamethoxazole Trimethoprim Combination Sulfamethoxazole Trimethoprim Combination Baylor Research Institute marketed Sulfonamide-dihydrofolate reductase inhibitor combination Dihydropteroate synthase; Dihydrofolate reductase
Sulfadoxine-pyrimethamine used for IPTi Sulfadoxine-pyrimethamine used for IPTi Swiss Tropical & Public Health Institute phase 3 Antifolate antimalarial combination Dihydropteroate synthase; Dihydrofolate reductase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Sulfonamide-dihydrofolate reductase inhibitor combination class)

  1. Baylor Research Institute · 1 drug in this class
  2. National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Sulfamethoxazole-Trimethoprim — Competitive Intelligence Brief. https://druglandscape.com/ci/sulfamethoxazole-trimethoprim. Accessed 2026-05-16.

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