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Standard: Ondansetron — Competitive Intelligence Brief

Standard: Ondansetron (Standard: Ondansetron) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Serotonin 5-HT3 receptor antagonist. Area: Oncology.

phase 3 Serotonin 5-HT3 receptor antagonist 5-HT3 receptor Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Standard: Ondansetron (Standard: Ondansetron) — CCTU. Ondansetron works by blocking serotonin receptors in the body, which helps to reduce nausea and vomiting.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Standard: Ondansetron TARGET Standard: Ondansetron CCTU phase 3 Serotonin 5-HT3 receptor antagonist 5-HT3 receptor
Trintellix vortioxetine Takeda marketed Serotonin modulator and stimulator (SMS); SSRI-like agent Serotonin transporter (SERT); 5-HT3 receptor; 5-HT1A receptor 2013-01-01
Metoclopramide, Granisetron, or Ondansetron Metoclopramide, Granisetron, or Ondansetron Sanofi marketed Antiemetic agents (dopamine antagonist, 5-HT3 receptor antagonists) Dopamine receptors (metoclopramide); 5-HT3 receptors (granisetron, ondansetron)
cardiac output changes with "ondansetron" cardiac output changes with "ondansetron" University Tunis El Manar marketed 5-HT3 receptor antagonist 5-HT3 receptor
Mirtazapine/SNRIs Mirtazapine/SNRIs Shanghai Mental Health Center marketed Tetracyclic antidepressant Alpha-2 adrenergic receptors, 5-HT2 receptors, 5-HT3 receptors
Ondansetron (ODT) Ondansetron (ODT) MonoSol Rx marketed 5-HT3 receptor antagonist 5-HT3 receptor
Kytril inj.+Kytril tab. Kytril inj.+Kytril tab. LG Life Sciences marketed 5-HT3 receptor antagonist 5-HT3 receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Serotonin 5-HT3 receptor antagonist class)

  1. CCTU · 1 drug in this class
  2. GlaxoSmithKline · 1 drug in this class
  3. RedHill Biopharma Limited · 1 drug in this class
  4. The First Affiliated Hospital of Xinxiang Medical College · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Standard: Ondansetron — Competitive Intelligence Brief. https://druglandscape.com/ci/standard-ondansetron. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing