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Standard: Ondansetron — Competitive Intelligence Brief
phase 3
Serotonin 5-HT3 receptor antagonist
5-HT3 receptor
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Standard: Ondansetron (Standard: Ondansetron) — CCTU. Ondansetron works by blocking serotonin receptors in the body, which helps to reduce nausea and vomiting.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Standard: Ondansetron TARGET | Standard: Ondansetron | CCTU | phase 3 | Serotonin 5-HT3 receptor antagonist | 5-HT3 receptor | |
| Trintellix | vortioxetine | Takeda | marketed | Serotonin modulator and stimulator (SMS); SSRI-like agent | Serotonin transporter (SERT); 5-HT3 receptor; 5-HT1A receptor | 2013-01-01 |
| Metoclopramide, Granisetron, or Ondansetron | Metoclopramide, Granisetron, or Ondansetron | Sanofi | marketed | Antiemetic agents (dopamine antagonist, 5-HT3 receptor antagonists) | Dopamine receptors (metoclopramide); 5-HT3 receptors (granisetron, ondansetron) | |
| cardiac output changes with "ondansetron" | cardiac output changes with "ondansetron" | University Tunis El Manar | marketed | 5-HT3 receptor antagonist | 5-HT3 receptor | |
| Mirtazapine/SNRIs | Mirtazapine/SNRIs | Shanghai Mental Health Center | marketed | Tetracyclic antidepressant | Alpha-2 adrenergic receptors, 5-HT2 receptors, 5-HT3 receptors | |
| Ondansetron (ODT) | Ondansetron (ODT) | MonoSol Rx | marketed | 5-HT3 receptor antagonist | 5-HT3 receptor | |
| Kytril inj.+Kytril tab. | Kytril inj.+Kytril tab. | LG Life Sciences | marketed | 5-HT3 receptor antagonist | 5-HT3 receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Serotonin 5-HT3 receptor antagonist class)
- CCTU · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
- RedHill Biopharma Limited · 1 drug in this class
- The First Affiliated Hospital of Xinxiang Medical College · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Standard: Ondansetron — Competitive Intelligence Brief. https://druglandscape.com/ci/standard-ondansetron. Accessed 2026-06-10.
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