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SSRI/Clomipramine — Competitive Intelligence Brief
phase 3
SSRI/SNRI
Serotonin transporter, Norepinephrine transporter
Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
SSRI/Clomipramine (SSRI/Clomipramine) — AstraZeneca. Clomipramine is a tricyclic antidepressant that works by inhibiting the reuptake of serotonin and norepinephrine.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| SSRI/Clomipramine TARGET | SSRI/Clomipramine | AstraZeneca | phase 3 | SSRI/SNRI | Serotonin transporter, Norepinephrine transporter | |
| Venlafaxine and Lamotrigine | Venlafaxine and Lamotrigine | University Health Network, Toronto | marketed | SNRI + anticonvulsant combination | Serotonin transporter, norepinephrine transporter, voltage-gated sodium channels, glutamate modulation | |
| Venlafaxine XR + Mirtazapine | Venlafaxine XR + Mirtazapine | National Institute of Mental Health (NIMH) | marketed | Antidepressant combination (SNRI + NaSSA) | Serotonin transporter, norepinephrine transporter, alpha-2 adrenergic receptors, 5-HT2 receptors, 5-HT3 receptors | |
| lidocaine+adjunct tramadol | lidocaine+adjunct tramadol | Bagcilar Training and Research Hospital | phase 3 | Local anesthetic, weak opioid agonist | Voltage-gated sodium channels, mu-opioid receptor, serotonin transporter, norepinephrine transporter | |
| desvenlafaxine SR | desvenlafaxine SR | Wyeth is now a wholly owned subsidiary of Pfizer | phase 3 | Serotonin-norepinephrine reuptake inhibitor (SNRI) | Serotonin transporter, Norepinephrine transporter | |
| desvenlafaxine succinate sustained release tablets | desvenlafaxine succinate sustained release tablets | Pfizer | phase 3 | Serotonin-norepinephrine reuptake inhibitor (SNRI) | Serotonin transporter, Norepinephrine transporter | |
| SSRI/Venlafaxine | SSRI/Venlafaxine | AstraZeneca | phase 3 | SSRI/Venlafaxine | Serotonin transporter, Norepinephrine transporter |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (SSRI/SNRI class)
- AstraZeneca · 1 drug in this class
- UCB Pharma · 1 drug in this class
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Cite this brief
Drug Landscape (2026). SSRI/Clomipramine — Competitive Intelligence Brief. https://druglandscape.com/ci/ssri-clomipramine. Accessed 2026-05-16.
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