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Sorafenib Ramp-Up Regimen — Competitive Intelligence Brief
marketed
Multi-kinase inhibitor
BRAF, VEGFR-2, VEGFR-3, PDGFR-β, FLT-3, c-KIT
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Sorafenib Ramp-Up Regimen (Sorafenib Ramp-Up Regimen) — University of Florida. Sorafenib is a multi-kinase inhibitor that blocks RAF, VEGFR, and PDGFR signaling to inhibit tumor cell proliferation and angiogenesis.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Sorafenib Ramp-Up Regimen TARGET | Sorafenib Ramp-Up Regimen | University of Florida | marketed | Multi-kinase inhibitor | BRAF, VEGFR-2, VEGFR-3, PDGFR-β, FLT-3, c-KIT | |
| Sorafenib Standard Dosing Regimen | Sorafenib Standard Dosing Regimen | University of Florida | marketed | Multi-kinase inhibitor | BRAF, VEGFR-2, VEGFR-3, PDGFR-β, FLT-3, c-KIT | |
| Sorafenib (SOR) | Sorafenib (SOR) | The University of Texas Health Science Center at San Antonio | marketed | Multi-kinase inhibitor; RAF/VEGFR/PDGFR inhibitor | RAF, VEGFR-2, VEGFR-3, PDGFR-β, FLT-3, c-KIT | |
| Sorafenib (SORA) | Sorafenib (SORA) | Nanfang Hospital, Southern Medical University | marketed | Multi-kinase inhibitor | RAF, VEGFR-2, VEGFR-3, PDGFR-β | |
| DEB-TACE plus Lenvatinib | DEB-TACE plus Lenvatinib | Guangxi Medical University | phase 3 | Combination therapy: locoregional chemotherapy + multi-kinase inhibitor | DEB-TACE: topoisomerase II (doxorubicin); Lenvatinib: FGFR, VEGFR, RET, KIT, PDGFR | |
| TAS-102, Regorafenib , Fruquintinib | TAS-102, Regorafenib , Fruquintinib | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | phase 3 | Nucleoside analog, Multi-kinase inhibitor, VEGFR2 inhibitor | Thymidylate synthase, VEGFR2 | |
| SKLB1028 | SKLB1028 | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | phase 3 | Multi-kinase inhibitor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Multi-kinase inhibitor class)
- University of Florida · 2 drugs in this class
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · 1 drug in this class
- Nanfang Hospital, Southern Medical University · 1 drug in this class
- Stephen Chan Lam · 1 drug in this class
- Sun Yat-sen University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Sorafenib Ramp-Up Regimen — Competitive Intelligence Brief. https://druglandscape.com/ci/sorafenib-ramp-up-regimen. Accessed 2026-05-16.
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