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Sorafenib Ramp-Up Regimen — Competitive Intelligence Brief

Sorafenib Ramp-Up Regimen (Sorafenib Ramp-Up Regimen) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Multi-kinase inhibitor. Area: Oncology.

marketed Multi-kinase inhibitor BRAF, VEGFR-2, VEGFR-3, PDGFR-β, FLT-3, c-KIT Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Sorafenib Ramp-Up Regimen (Sorafenib Ramp-Up Regimen) — University of Florida. Sorafenib is a multi-kinase inhibitor that blocks RAF, VEGFR, and PDGFR signaling to inhibit tumor cell proliferation and angiogenesis.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Sorafenib Ramp-Up Regimen TARGET Sorafenib Ramp-Up Regimen University of Florida marketed Multi-kinase inhibitor BRAF, VEGFR-2, VEGFR-3, PDGFR-β, FLT-3, c-KIT
Sorafenib Standard Dosing Regimen Sorafenib Standard Dosing Regimen University of Florida marketed Multi-kinase inhibitor BRAF, VEGFR-2, VEGFR-3, PDGFR-β, FLT-3, c-KIT
Sorafenib (SOR) Sorafenib (SOR) The University of Texas Health Science Center at San Antonio marketed Multi-kinase inhibitor; RAF/VEGFR/PDGFR inhibitor RAF, VEGFR-2, VEGFR-3, PDGFR-β, FLT-3, c-KIT
Sorafenib (SORA) Sorafenib (SORA) Nanfang Hospital, Southern Medical University marketed Multi-kinase inhibitor RAF, VEGFR-2, VEGFR-3, PDGFR-β
DEB-TACE plus Lenvatinib DEB-TACE plus Lenvatinib Guangxi Medical University phase 3 Combination therapy: locoregional chemotherapy + multi-kinase inhibitor DEB-TACE: topoisomerase II (doxorubicin); Lenvatinib: FGFR, VEGFR, RET, KIT, PDGFR
TAS-102, Regorafenib , Fruquintinib TAS-102, Regorafenib , Fruquintinib Suzhou Suncadia Biopharmaceuticals Co., Ltd. phase 3 Nucleoside analog, Multi-kinase inhibitor, VEGFR2 inhibitor Thymidylate synthase, VEGFR2
SKLB1028 SKLB1028 CSPC ZhongQi Pharmaceutical Technology Co., Ltd. phase 3 Multi-kinase inhibitor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Multi-kinase inhibitor class)

  1. University of Florida · 2 drugs in this class
  2. CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · 1 drug in this class
  3. Nanfang Hospital, Southern Medical University · 1 drug in this class
  4. Stephen Chan Lam · 1 drug in this class
  5. Sun Yat-sen University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Sorafenib Ramp-Up Regimen — Competitive Intelligence Brief. https://druglandscape.com/ci/sorafenib-ramp-up-regimen. Accessed 2026-05-16.

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