Sonidegib Phosphate Capsules — Competitive Intelligence Brief

Sonidegib Phosphate Capsules (Sonidegib Phosphate Capsules) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Hedgehog pathway inhibitor. Area: Oncology.

marketed Hedgehog pathway inhibitor Smoothened (SMO) Oncology Small molecule

Target snapshot

Sonidegib Phosphate Capsules (Sonidegib Phosphate Capsules) — Jemincare. Sonidegib is a Hedgehog pathway inhibitor that blocks Smoothened (SMO) signaling to suppress aberrant cell proliferation driven by Hedgehog pathway activation.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Sonidegib Phosphate Capsules TARGET	Sonidegib Phosphate Capsules	Jemincare	marketed	Hedgehog pathway inhibitor	Smoothened (SMO)
Daurismo	Glasdegib Maleate	Pfizer	marketed	Hedgehog pathway inhibitor	Smoothened (transmembrane protein)	2018-01-01
Daurismo	glasdegib	Pfizer	marketed	Hedgehog Pathway Inhibitor [EPC]	Smoothened homolog	2018-01-01
GLASDEGIB	GLASDEGIB		marketed	Hedgehog Pathway Inhibitor [EPC]		2018-01-01
Erivedge	vismodegib	Roche	marketed	Hedgehog Pathway Inhibitor [EPC]	Smoothened	2012-01-01
ERIVEDGE	ERIVEDGE	University Hospital, Lille	marketed	Hedgehog pathway inhibitor	Smoothened (SMO)
Treatment with vismodegib	Treatment with vismodegib	University Hospital, Bordeaux	marketed	Hedgehog pathway inhibitor	Smoothened (SMO)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Hedgehog pathway inhibitor class)

1. Jemincare · 1 drug in this class
2. Pfizer · 1 drug in this class
3. University Hospital, Bordeaux · 1 drug in this class
4. University Hospital, Lille · 1 drug in this class