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SONIDEGIB — Competitive Intelligence Brief
marketed
Smoothened
Small molecule
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Target snapshot
SONIDEGIB (SONIDEGIB). Sonidegib inhibits the Hh pathway by binding to and blocking Smoothened, a key transmembrane protein.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| SONIDEGIB TARGET | SONIDEGIB | marketed | Smoothened | 2015-01-01 | ||
| Daurismo | glasdegib | Pfizer | marketed | Hedgehog Pathway Inhibitor [EPC] | Smoothened homolog | 2018-01-01 |
| Daurismo | Glasdegib Maleate | Pfizer | marketed | Hedgehog pathway inhibitor | Smoothened (transmembrane protein) | 2018-01-01 |
| Erivedge | vismodegib | Roche | marketed | Hedgehog Pathway Inhibitor [EPC] | Smoothened | 2012-01-01 |
| Sonidegib Phosphate Capsules | Sonidegib Phosphate Capsules | Jemincare | marketed | Hedgehog pathway inhibitor | Smoothened (SMO) | |
| ERIVEDGE | ERIVEDGE | University Hospital, Lille | marketed | Hedgehog pathway inhibitor | Smoothened (SMO) | |
| Treatment with vismodegib | Treatment with vismodegib | University Hospital, Bordeaux | marketed | Hedgehog pathway inhibitor | Smoothened (SMO) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape
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Cite this brief
Drug Landscape (2026). SONIDEGIB — Competitive Intelligence Brief. https://druglandscape.com/ci/sonidegib. Accessed 2026-05-13.
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