Who are Sodium Hyaluronate Ophthalmic 0.4%'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Systane (r) Ultra, carboxymethylcellulose 0.5% +glycerin 0.9%, methylcellulose 0.5%, TJO-018 (HA 0.15%), Retaine™, PEG- 400 based artificial tear.

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Last reviewed 2026-05-16 · How we verify

Sodium Hyaluronate Ophthalmic 0.4% — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Sodium Hyaluronate Ophthalmic 0.4% (Sodium Hyaluronate Ophthalmic 0.4%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Artificial tear / Ocular lubricant. Area: Ophthalmology.

marketed Artificial tear / Ocular lubricant Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

Sodium Hyaluronate Ophthalmic 0.4% (Sodium Hyaluronate Ophthalmic 0.4%) — Laboratorios Sophia S.A de C.V.. Sodium hyaluronate acts as a lubricating and hydrating agent that coats the ocular surface to relieve dry eye symptoms.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Sodium Hyaluronate Ophthalmic 0.4% TARGET	Sodium Hyaluronate Ophthalmic 0.4%	Laboratorios Sophia S.A de C.V.	marketed	Artificial tear / Ocular lubricant
Systane (r) Ultra	Systane (r) Ultra	ORA, Inc.	marketed	Artificial tear / ocular lubricant
carboxymethylcellulose 0.5% +glycerin 0.9%	carboxymethylcellulose 0.5% +glycerin 0.9%	Allergan	marketed	Artificial tear / ocular lubricant
methylcellulose 0.5%	methylcellulose 0.5%	Clinica Oftamologica Zona Sul	marketed	Artificial tear / Ocular lubricant
TJO-018 (HA 0.15%)	TJO-018 (HA 0.15%)	Taejoon Pharmaceutical Co., Ltd.	marketed	Artificial tear / Ocular lubricant	Ocular surface (non-receptor mediated)
Retaine™	Retaine™	Ocusoft, Inc.	marketed	Artificial tear / ocular lubricant
PEG- 400 based artificial tear	PEG- 400 based artificial tear	Bp Consulting, Inc	marketed	Artificial tear / Ocular lubricant

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Artificial tear / Ocular lubricant class)

Laboratorios Sophia S.A de C.V. · 7 drugs in this class
Allergan · 3 drugs in this class
University of Waterloo · 2 drugs in this class
University of California, Berkeley · 2 drugs in this class
Bp Consulting, Inc · 1 drug in this class
Chong Kun Dang Pharmaceutical · 1 drug in this class
Clinica Oftamologica Zona Sul · 1 drug in this class
Fundação Altino Ventura · 1 drug in this class
Medical University of South Carolina · 1 drug in this class
Ocuwize LTD · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Sodium Hyaluronate Ophthalmic 0.4% — Competitive Intelligence Brief. https://druglandscape.com/ci/sodium-hyaluronate-ophthalmic-0-4. Accessed 2026-05-16.

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