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simvastatin and ezetimibe — Competitive Intelligence Brief
marketed
Statin and cholesterol absorption inhibitor combination
HMG-CoA reductase and NPC1L1 transporter
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
simvastatin and ezetimibe (simvastatin and ezetimibe) — UMC Utrecht. Simvastatin inhibits cholesterol synthesis while ezetimibe blocks dietary cholesterol absorption, together reducing LDL cholesterol levels.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| simvastatin and ezetimibe TARGET | simvastatin and ezetimibe | UMC Utrecht | marketed | Statin and cholesterol absorption inhibitor combination | HMG-CoA reductase and NPC1L1 transporter | |
| Rosuvastatin and Ezetimibe | Rosuvastatin and Ezetimibe | Hanmi Pharmaceutical Company Limited | marketed | Statin and ezetimibe combination | HMG-CoA reductase and NPC1L1 transporter | |
| Atorvastatin, Ezetimibe | Atorvastatin, Ezetimibe | Abant Izzet Baysal University | marketed | Statin and cholesterol absorption inhibitor combination | HMG-CoA reductase; NPC1L1 transporter |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Statin and cholesterol absorption inhibitor combination class)
- Abant Izzet Baysal University · 1 drug in this class
- UMC Utrecht · 1 drug in this class
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Cite this brief
Drug Landscape (2026). simvastatin and ezetimibe — Competitive Intelligence Brief. https://druglandscape.com/ci/simvastatin-and-ezetimibe. Accessed 2026-05-14.
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