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simvastatin and ezetimibe — Competitive Intelligence Brief

simvastatin and ezetimibe (simvastatin and ezetimibe) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Statin and cholesterol absorption inhibitor combination. Area: Cardiovascular.

marketed Statin and cholesterol absorption inhibitor combination HMG-CoA reductase and NPC1L1 transporter Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

simvastatin and ezetimibe (simvastatin and ezetimibe) — UMC Utrecht. Simvastatin inhibits cholesterol synthesis while ezetimibe blocks dietary cholesterol absorption, together reducing LDL cholesterol levels.

Comparator set (2 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
simvastatin and ezetimibe TARGET simvastatin and ezetimibe UMC Utrecht marketed Statin and cholesterol absorption inhibitor combination HMG-CoA reductase and NPC1L1 transporter
Rosuvastatin and Ezetimibe Rosuvastatin and Ezetimibe Hanmi Pharmaceutical Company Limited marketed Statin and ezetimibe combination HMG-CoA reductase and NPC1L1 transporter
Atorvastatin, Ezetimibe Atorvastatin, Ezetimibe Abant Izzet Baysal University marketed Statin and cholesterol absorption inhibitor combination HMG-CoA reductase; NPC1L1 transporter

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Statin and cholesterol absorption inhibitor combination class)

  1. Abant Izzet Baysal University · 1 drug in this class
  2. UMC Utrecht · 1 drug in this class

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Cite this brief

Drug Landscape (2026). simvastatin and ezetimibe — Competitive Intelligence Brief. https://druglandscape.com/ci/simvastatin-and-ezetimibe. Accessed 2026-05-14.

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