Who are SGX301 (synthetic hypericin)'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Rose Bengal, aminolevulinic acid (ALA), Hemoporfin PDT, verteporfin, bevacizumab, triamcinolone acetonide, 5-Methoxypsoralen, padeliporfin VTP.

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Last reviewed 2026-05-16 · How we verify

SGX301 (synthetic hypericin) — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

SGX301 (synthetic hypericin) (SGX301 (synthetic hypericin)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Photosensitizer. Area: Oncology; Dermatology.

phase 3 Photosensitizer Hypericin (photosensitizing agent); generates ROS upon light activation Oncology; Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

SGX301 (synthetic hypericin) (SGX301 (synthetic hypericin)) — Soligenix. SGX301 is a synthetic hypericin that generates reactive oxygen species upon light activation to destroy targeted cells, particularly in photodynamic therapy applications.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
SGX301 (synthetic hypericin) TARGET	SGX301 (synthetic hypericin)	Soligenix	phase 3	Photosensitizer	Hypericin (photosensitizing agent); generates ROS upon light activation
Rose Bengal	Rose Bengal	University of California, San Francisco	marketed	Photosensitizer
aminolevulinic acid (ALA)	aminolevulinic acid (ALA)	University of California, Davis	marketed	Photosensitizer	Protoporphyrin IX (endogenous photosensitizer generated from ALA)
Hemoporfin PDT	Hemoporfin PDT	Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.	marketed	Photosensitizer	Porphyrin-based photosensitizer (non-receptor mediated)
verteporfin, bevacizumab, triamcinolone acetonide	verteporfin, bevacizumab, triamcinolone acetonide	Shahid Beheshti University of Medical Sciences	phase 3	photosensitizer, monoclonal antibody, corticosteroid	VEGF-A, VEGF receptor
5-Methoxypsoralen	5-Methoxypsoralen	Medical University of Vienna	phase 3	Furocoumarin photosensitizer	DNA (intercalating agent)
padeliporfin VTP	padeliporfin VTP	Steba Biotech S.A.	phase 3	Photosensitizer

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Photosensitizer class)

Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. · 2 drugs in this class
Soligenix · 1 drug in this class
Steba Biotech S.A. · 1 drug in this class
University of California, Davis · 1 drug in this class
University of California, San Francisco · 1 drug in this class

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Cite this brief

Drug Landscape (2026). SGX301 (synthetic hypericin) — Competitive Intelligence Brief. https://druglandscape.com/ci/sgx301-synthetic-hypericin. Accessed 2026-05-16.

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