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Selective serotonin reuptake inhibitors — Competitive Intelligence Brief
marketed
Selective serotonin reuptake inhibitor
Serotonin transporter (SERT)
Psychiatry / Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Selective serotonin reuptake inhibitors (Selective serotonin reuptake inhibitors) — Faculdade de Medicina do ABC. SSRIs block the reuptake of serotonin at the presynaptic neuron, increasing serotonin concentration in the synaptic cleft.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Selective serotonin reuptake inhibitors TARGET | Selective serotonin reuptake inhibitors | Faculdade de Medicina do ABC | marketed | Selective serotonin reuptake inhibitor | Serotonin transporter (SERT) | |
| Lexapro | escitalopram | Generic (originally Lundbeck/Forest) | marketed | Selective Serotonin Reuptake Inhibitor (SSRI) | Serotonin (5-HT) reuptake transporter | 2002-08-14 |
| Zoloft | sertraline | Pfizer Inc. | marketed | SSRI (Selective serotonin reuptake inhibitor) | Cytochrome P450 2C19, Melanocortin receptor 5, 5-hydroxytryptamine receptor 2A | 1991-12-30 |
| Prozac | fluoxetine | Eli Lilly and Company | marketed | Selective Serotonin Reuptake Inhibitor (SSRI) | Serotonin reuptake transporter | 1987-12-29 |
| Track A | Track A | ATS Clinical Research | marketed | Selective serotonin reuptake inhibitor | Serotonin transporter | |
| sertraline fluvoxamine | sertraline fluvoxamine | Second Affiliated Hospital, School of Medicine, Zhejiang University | marketed | Selective serotonin reuptake inhibitor (SSRI) | Serotonin transporter (SERT) | |
| Citalopram HCl | Citalopram HCl | Universitaire Ziekenhuizen KU Leuven | marketed | Selective serotonin reuptake inhibitor (SSRI) | Serotonin transporter (SERT) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Selective serotonin reuptake inhibitor class)
- Shanghai Mental Health Center · 2 drugs in this class
- ATS Clinical Research · 2 drugs in this class
- Faculdade de Medicina do ABC · 1 drug in this class
- InnoPharmax Inc. · 1 drug in this class
- Istituto Auxologico Italiano · 1 drug in this class
- Novartis · 1 drug in this class
- Sichuan Baili Pharmaceutical Co., Ltd. · 1 drug in this class
- Eurofarma Laboratorios S.A. · 1 drug in this class
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- Selective serotonin reuptake inhibitors CI watch — RSS
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Cite this brief
Drug Landscape (2026). Selective serotonin reuptake inhibitors — Competitive Intelligence Brief. https://druglandscape.com/ci/selective-serotonin-reuptake-inhibitors. Accessed 2026-05-16.
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