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Sedation by ketamine — Competitive Intelligence Brief
phase 3
Anesthetic
NMDA receptor
Anesthesiology
Small molecule
Live · refreshed every 30 min
Target snapshot
Sedation by ketamine (Sedation by ketamine) — University Hospital, Montpellier. Ketamine acts as an NMDA receptor antagonist, blocking the action of glutamate at the NMDA receptor.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Sedation by ketamine TARGET | Sedation by ketamine | University Hospital, Montpellier | phase 3 | Anesthetic | NMDA receptor | |
| Namenda | MEMANTINE | AbbVie | marketed | N-methyl-D-aspartate Receptor Antagonist | Glutamate NMDA receptor; GRIN1/GRIN2A | 2003-01-01 |
| Felbatol | FELBAMATE | Mylan Speciality Lp | marketed | Anti-epileptic Agent [EPC] | NMDA receptor-ionophore complex | 1993-01-01 |
| QUINIDINE | QUINIDINE | marketed | sigma-1 receptor, NMDA receptor, CYP2D6 | 1950-01-01 | ||
| Methadone Hydrochloride | METHADONE | Specgx Llc | marketed | Opioid Agonist | mu-opioid receptors, NMDA receptor | 1947-01-01 |
| Midazolam+Ketamine Combination | Midazolam+Ketamine Combination | Universidad de Cartagena | marketed | Sedative-hypnotic and dissociative anesthetic combination | GABA-A receptor (midazolam); NMDA receptor (ketamine) | |
| Magnesium Sulfate, Heptahydrate | Magnesium Sulfate, Heptahydrate | University of Utah | marketed | Electrolyte supplement / anticonvulsant / bronchodilator | NMDA receptor, voltage-gated calcium channels |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Anesthetic class)
- Express Specialty Pharmacy · 1 drug in this class
- Nantes University Hospital · 1 drug in this class
- The University of Texas Health Science Center, Houston · 1 drug in this class
- Universidad de Colima · 1 drug in this class
- University Hospital, Montpellier · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Sedation by ketamine — Competitive Intelligence Brief. https://druglandscape.com/ci/sedation-by-ketamine. Accessed 2026-06-10.
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