Who are SAGE-547's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Qalsody, Amondys 45, Vyondys 53, Exondys 51, Kynamro, PF-07852352 Influenza saRNA 1.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-15 · How we verify

SAGE-547 — Competitive Intelligence Brief

SAGE-547 (SAGE-547) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: antisense oligonucleotide. Area: Neurology.

phase 3 antisense oligonucleotide GABA_A receptor alpha 1 subunit Neurology Small molecule Live · refreshed every 30 min

Target snapshot

SAGE-547 (SAGE-547) — Supernus Pharmaceuticals, Inc.. SAGE-547 is an intravenous formulation of an antisense oligonucleotide that targets the GABA_A receptor alpha 1 subunit.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
SAGE-547 TARGET	SAGE-547	Supernus Pharmaceuticals, Inc.	phase 3	antisense oligonucleotide	GABA_A receptor alpha 1 subunit
Qalsody	TOFERSEN	Biogen Ma	marketed	Antisense Oligonucleotide [EPC]	Superoxide dismutase 1 (SOD1) mRNA	2023-01-01
Amondys 45	CASIMERSEN	Sarepta	marketed	Antisense Oligonucleotide [EPC]	exon 53 of dystrophin pre-mRNA	2021-01-01
Vyondys 53	GOLODIRSEN	Sarepta	marketed	Antisense Oligonucleotide [EPC]	exon 53 of dystrophin pre-mRNA	2019-01-01
Exondys 51	ETEPLIRSEN	Sarepta	marketed	Antisense Oligonucleotide [EPC]	exon 51 of dystrophin pre-mRNA	2016-01-01
Kynamro	MIPOMERSEN	Kastle Theraps Llc	marketed	Antisense Oligonucleotide		2013-01-01
PF-07852352 Influenza saRNA 1	pf-07852352-influenza-sarna-1	Pfizer	marketed	antisense oligonucleotide	influenza virus

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (antisense oligonucleotide class)

Acerta Pharma BV · 1 drug in this class
Avidity Biosciences, Inc. · 1 drug in this class
Hoffmann-La Roche · 1 drug in this class
Ionis Pharmaceuticals, Inc. · 1 drug in this class
Pfizer · 1 drug in this class
Supernus Pharmaceuticals, Inc. · 1 drug in this class
Sylentis, S.A. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). SAGE-547 — Competitive Intelligence Brief. https://druglandscape.com/ci/sage-547. Accessed 2026-05-15.

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