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Rucacuzumab plus standard therapy — Competitive Intelligence Brief
marketed
Monoclonal antibody; complement inhibitor
C1q (complement component 1q)
Immunology; Rheumatology
Small molecule
Live · refreshed every 30 min
Target snapshot
Rucacuzumab plus standard therapy (Rucacuzumab plus standard therapy) — Peking Union Medical College Hospital. Rucacuzumab is a monoclonal antibody that binds to complement component C1q to inhibit the classical complement pathway, reducing inflammatory and immune-mediated tissue damage.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Rucacuzumab plus standard therapy TARGET | Rucacuzumab plus standard therapy | Peking Union Medical College Hospital | marketed | Monoclonal antibody; complement inhibitor | C1q (complement component 1q) | |
| Veopoz | POZELIMAB | Regeneron | marketed | Complement Inhibitor [EPC] | Complement C5 | 2023-01-01 |
| AVACINCAPTAD PEGOL SODIUM | AVACINCAPTAD PEGOL SODIUM | marketed | Complement Inhibitors | Complement C5 | 2023-01-01 | |
| Ultomiris | RAVULIZUMAB | AstraZeneca | marketed | Complement Inhibitor [EPC] | Complement C5 | 2018-01-01 |
| H5G1.1 | ECULIZUMAB | AstraZeneca | marketed | Complement Inhibitor [EPC] | C5 | 2007-01-01 |
| BKEMV | ECULIZUMAB-AEEB | AMGEN INC | marketed | Complement Inhibitor [EPC] | ||
| Eculizumab+IVMP | Eculizumab+IVMP | Chinese PLA General Hospital | marketed | Complement inhibitor + corticosteroid combination | Complement C5 + glucocorticoid receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — AVACINCAPTAD PEGOL SODIUM · 8236773 · Method of Use · US
- — AVACINCAPTAD PEGOL SODIUM · 9617546 · Compound · US
- — AVACINCAPTAD PEGOL SODIUM · 7579456 · Compound · US
- — AVACINCAPTAD PEGOL SODIUM · 11491176 · Method of Use · US
- — AVACINCAPTAD PEGOL SODIUM · 11273171 · Method of Use · US
- — AVACINCAPTAD PEGOL SODIUM · 12016875 · Method of Use · US
Sponsor landscape (Monoclonal antibody; complement inhibitor class)
- Peking Union Medical College Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Rucacuzumab plus standard therapy — Competitive Intelligence Brief. https://druglandscape.com/ci/rucacuzumab-plus-standard-therapy. Accessed 2026-05-17.
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