Who are rThrombin's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): FIX, Albutrepenonacog Alfa 1 UNT [IDELVION], Kogenate (BAY14-2222), OBIZUR, Eptacog alfa (NovoSeven), RIXUBIS: On-Demand.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

rThrombin — Competitive Intelligence Brief

rThrombin (rThrombin) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Recombinant coagulation factor. Area: Hematology.

phase 3 Recombinant coagulation factor Fibrinogen (Factor I) Hematology Biologic Live · refreshed every 30 min

Target snapshot

rThrombin (rThrombin) — ZymoGenetics. rThrombin is a recombinant human thrombin that directly converts fibrinogen to fibrin to promote blood clotting and hemostasis.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
rThrombin TARGET	rThrombin	ZymoGenetics	phase 3	Recombinant coagulation factor	Fibrinogen (Factor I)
FIX	FIX	Bioverativ Therapeutics Inc.	marketed	Recombinant coagulation factor replacement	Factor IX (coagulation cascade)
Albutrepenonacog Alfa 1 UNT [IDELVION]	Albutrepenonacog Alfa 1 UNT [IDELVION]	National Taiwan University Hospital	marketed	Recombinant coagulation factor (Factor IX fusion protein)	Factor IX (coagulation factor IX)
Kogenate (BAY14-2222)	Kogenate (BAY14-2222)	Bayer	marketed	Recombinant coagulation factor VIII	Coagulation factor VIII
OBIZUR	OBIZUR	Baxalta now part of Shire	marketed	Recombinant coagulation factor VIII	Coagulation factor VIII
Eptacog alfa (NovoSeven)	Eptacog alfa (NovoSeven)	Novo Nordisk A/S	marketed	Recombinant coagulation factor	Tissue factor (TF) / Factor X
RIXUBIS: On-Demand	RIXUBIS: On-Demand	Baxalta now part of Shire	marketed	Recombinant coagulation factor	Coagulation Factor IX (FIX)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Recombinant coagulation factor class)

Baxalta now part of Shire · 2 drugs in this class
AryoGen Pharmed Co. · 1 drug in this class
Nicoletta C Machin · 1 drug in this class
Novo Nordisk A/S · 1 drug in this class
ZymoGenetics · 1 drug in this class

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Cite this brief

Drug Landscape (2026). rThrombin — Competitive Intelligence Brief. https://druglandscape.com/ci/rthrombin. Accessed 2026-05-14.

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