Who are rituximab+chlorambucil's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Venetoclax; Rituximab, Columvi, Lunsumio, Ocrevus, Gazyva, Kesimpta.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-17 · How we verify

rituximab+chlorambucil — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

rituximab+chlorambucil (rituximab+chlorambucil) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Monoclonal antibody + alkylating agent. Area: Oncology.

phase 3 Monoclonal antibody + alkylating agent CD20 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

rituximab+chlorambucil (rituximab+chlorambucil) — International Extranodal Lymphoma Study Group (IELSG). Rituximab is a monoclonal antibody that targets and depletes CD20-positive B cells, while chlorambucil is an alkylating agent that interferes with DNA replication.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
rituximab+chlorambucil TARGET	rituximab+chlorambucil	International Extranodal Lymphoma Study Group (IELSG)	phase 3	Monoclonal antibody + alkylating agent	CD20
Venetoclax; Rituximab	venetoclax-rituximab	Pfizer	marketed	BCL-2 inhibitor (venetoclax); Monoclonal antibody (rituximab)	BCL-2 (venetoclax); CD20 (rituximab)	N/A
Columvi	glofitamab	Roche	marketed	Bispecific CD20-directed CD3 T Cell Engager [EPC]	B-lymphocyte antigen CD20	2023-01-01
Lunsumio	MOSUNETUZUMAB	Roche	marketed		B-lymphocyte antigen CD20	2022-01-01
Ocrevus	OCRELIZUMAB	Roche	marketed	CD20-directed Cytolytic Antibody [EPC]	B-lymphocyte antigen CD20	2017-01-01
Gazyva	obinutuzumab	Roche	marketed	CD20-directed Cytolytic Antibody [EPC]	B-lymphocyte antigen CD20	2013-01-01
Kesimpta	OFATUMUMAB	Novartis	marketed	Anti-CD20 monoclonal antibody	CD20	2009-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Monoclonal antibody + alkylating agent class)

International Extranodal Lymphoma Study Group (IELSG) · 1 drug in this class

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Cite this brief

Drug Landscape (2026). rituximab+chlorambucil — Competitive Intelligence Brief. https://druglandscape.com/ci/rituximab-chlorambucil. Accessed 2026-05-17.

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