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Rituximab and Hyaluronidase Human — Competitive Intelligence Brief

Rituximab and Hyaluronidase Human (Rituximab and Hyaluronidase Human) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Monoclonal antibody with recombinant human hyaluronidase. Area: Oncology, Immunology.

phase 3 Monoclonal antibody with recombinant human hyaluronidase CD20 Oncology, Immunology Biologic Live · refreshed every 30 min

Target snapshot

Rituximab and Hyaluronidase Human (Rituximab and Hyaluronidase Human) — National Cancer Institute (NCI). Rituximab targets CD20 on B cells to deplete them, while hyaluronidase enables subcutaneous delivery by breaking down hyaluronic acid in subcutaneous tissue.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Rituximab and Hyaluronidase Human TARGET Rituximab and Hyaluronidase Human National Cancer Institute (NCI) phase 3 Monoclonal antibody with recombinant human hyaluronidase CD20
Venetoclax; Rituximab venetoclax-rituximab Pfizer marketed BCL-2 inhibitor (venetoclax); Monoclonal antibody (rituximab) BCL-2 (venetoclax); CD20 (rituximab) N/A
Columvi glofitamab Roche marketed Bispecific CD20-directed CD3 T Cell Engager [EPC] B-lymphocyte antigen CD20 2023-01-01
Lunsumio MOSUNETUZUMAB Roche marketed B-lymphocyte antigen CD20 2022-01-01
Ocrevus OCRELIZUMAB Roche marketed CD20-directed Cytolytic Antibody [EPC] B-lymphocyte antigen CD20 2017-01-01
Gazyva obinutuzumab Roche marketed CD20-directed Cytolytic Antibody [EPC] B-lymphocyte antigen CD20 2013-01-01
Kesimpta OFATUMUMAB Novartis marketed Anti-CD20 monoclonal antibody CD20 2009-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Monoclonal antibody with recombinant human hyaluronidase class)

  1. Masonic Cancer Center, University of Minnesota · 1 drug in this class
  2. National Cancer Institute (NCI) · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Rituximab and Hyaluronidase Human — Competitive Intelligence Brief. https://druglandscape.com/ci/rituximab-and-hyaluronidase-human. Accessed 2026-05-18.

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