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Rituximab and Hyaluronidase Human — Competitive Intelligence Brief
phase 3
Monoclonal antibody with recombinant human hyaluronidase
CD20
Oncology, Immunology
Biologic
Live · refreshed every 30 min
Target snapshot
Rituximab and Hyaluronidase Human (Rituximab and Hyaluronidase Human) — National Cancer Institute (NCI). Rituximab targets CD20 on B cells to deplete them, while hyaluronidase enables subcutaneous delivery by breaking down hyaluronic acid in subcutaneous tissue.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Rituximab and Hyaluronidase Human TARGET | Rituximab and Hyaluronidase Human | National Cancer Institute (NCI) | phase 3 | Monoclonal antibody with recombinant human hyaluronidase | CD20 | |
| Venetoclax; Rituximab | venetoclax-rituximab | Pfizer | marketed | BCL-2 inhibitor (venetoclax); Monoclonal antibody (rituximab) | BCL-2 (venetoclax); CD20 (rituximab) | N/A |
| Columvi | glofitamab | Roche | marketed | Bispecific CD20-directed CD3 T Cell Engager [EPC] | B-lymphocyte antigen CD20 | 2023-01-01 |
| Lunsumio | MOSUNETUZUMAB | Roche | marketed | B-lymphocyte antigen CD20 | 2022-01-01 | |
| Ocrevus | OCRELIZUMAB | Roche | marketed | CD20-directed Cytolytic Antibody [EPC] | B-lymphocyte antigen CD20 | 2017-01-01 |
| Gazyva | obinutuzumab | Roche | marketed | CD20-directed Cytolytic Antibody [EPC] | B-lymphocyte antigen CD20 | 2013-01-01 |
| Kesimpta | OFATUMUMAB | Novartis | marketed | Anti-CD20 monoclonal antibody | CD20 | 2009-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Monoclonal antibody with recombinant human hyaluronidase class)
- Masonic Cancer Center, University of Minnesota · 1 drug in this class
- National Cancer Institute (NCI) · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Rituximab and Hyaluronidase Human — Competitive Intelligence Brief. https://druglandscape.com/ci/rituximab-and-hyaluronidase-human. Accessed 2026-05-18.
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