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rifapentine + isoniazid — Competitive Intelligence Brief
phase 3
Antitubercular
Infectious Diseases
Small molecule
Live · refreshed every 30 min
Target snapshot
rifapentine + isoniazid (rifapentine + isoniazid) — The Aurum Institute NPC. Rifapentine inhibits the synthesis of mycolic acid in Mycobacterium tuberculosis, while isoniazid inhibits the synthesis of mycolic acid and the metabolism of fatty acids.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| rifapentine + isoniazid TARGET | rifapentine + isoniazid | The Aurum Institute NPC | phase 3 | Antitubercular | ||
| RNTCP Category I treatment for 9months | RNTCP Category I treatment for 9months | All India Institute of Medical Sciences | phase 3 | Antitubercular | InhA (Isoniazid target) | |
| RIFINAH © | RIFINAH © | Assistance Publique - Hôpitaux de Paris | phase 3 | Antitubercular | RNA polymerase beta-subunit | |
| Rifampin-free regimen | Rifampin-free regimen | Nantes University Hospital | phase 3 | Antitubercular | ||
| isoniazid , randomized, open label | isoniazid , randomized, open label | National Taiwan University Hospital | phase 3 | Antitubercular agent | InhA | |
| isoniazid and rifapentine | isoniazid and rifapentine | National Taiwan University Hospital | phase 3 | Antitubercular agent | InhA (enoyl-acyl carrier protein reductase), RNA polymerase | |
| Tuberculosis treatment | Tuberculosis treatment | National Institute of Allergy and Infectious Diseases (NIAID) | phase 3 | Antitubercular | InhA |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antitubercular class)
- All India Institute of Medical Sciences · 2 drugs in this class
- Assistance Publique - Hôpitaux de Paris · 1 drug in this class
- LigaChem Biosciences, Inc. · 1 drug in this class
- Nantes University Hospital · 1 drug in this class
- National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class
- The Aurum Institute NPC · 1 drug in this class
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Cite this brief
Drug Landscape (2026). rifapentine + isoniazid — Competitive Intelligence Brief. https://druglandscape.com/ci/rifapentine-isoniazid. Accessed 2026-05-16.
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