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rhBNP — Competitive Intelligence Brief
marketed
Natriuretic peptide
Natriuretic peptide receptor-A (NPR-A)
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
rhBNP (rhBNP) — LI ZHAO. rhBNP (recombinant human B-type natriuretic peptide) mimics the body's natural natriuretic peptide to promote vasodilation, reduce cardiac preload and afterload, and improve hemodynamics in acute decompensated heart failure.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| rhBNP TARGET | rhBNP | LI ZHAO | marketed | Natriuretic peptide | Natriuretic peptide receptor-A (NPR-A) | |
| Natrecor | NESIRITIDE | Scios Llc | marketed | Natriuretic Peptide | Atrial natriuretic peptide receptor 1 | 2001-01-01 |
| Nesiritide (Natrecor) | Nesiritide (Natrecor) | M.D. Anderson Cancer Center | marketed | Natriuretic peptide | Natriuretic peptide receptor-A (NPR-A) | |
| nesiritide, furosemide | nesiritide, furosemide | Scios, Inc. | marketed | Natriuretic peptide analog and loop diuretic combination | Natriuretic peptide receptor-A (NPR-A) and Na-K-2Cl cotransporter | |
| recombinant human BNP(1-32) | recombinant human BNP(1-32) | VA Office of Research and Development | marketed | Natriuretic peptide | Natriuretic peptide receptor-A (NPR-A) | |
| Carperitide heart failure therapy | Carperitide heart failure therapy | Nara Medical University | marketed | Natriuretic peptide | Natriuretic peptide receptor-A (NPR-A) | |
| recombinant B-type, natriuretic peptide | recombinant B-type, natriuretic peptide | University of Texas Southwestern Medical Center | marketed | Natriuretic peptides | Natriuretic peptide receptor-A (NPR-A) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Natriuretic peptide class)
- LI ZHAO · 1 drug in this class
- M.D. Anderson Cancer Center · 1 drug in this class
- Nara Medical University · 1 drug in this class
- Scios, Inc. · 1 drug in this class
- VA Office of Research and Development · 1 drug in this class
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Cite this brief
Drug Landscape (2026). rhBNP — Competitive Intelligence Brief. https://druglandscape.com/ci/rhbnp. Accessed 2026-05-13.
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