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Recombinant Von Willebrand factor — Competitive Intelligence Brief

Recombinant Von Willebrand factor (Recombinant Von Willebrand factor) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Recombinant coagulation factor. Area: Hematology.

marketed Recombinant coagulation factor Von Willebrand factor receptor (GPIb-IX-V complex on platelets); Factor VIII binding site Hematology Small molecule Live · refreshed every 30 min

Target snapshot

Recombinant Von Willebrand factor (Recombinant Von Willebrand factor) — Nicoletta C Machin. Recombinant von Willebrand factor replaces or supplements the natural von Willebrand factor protein to restore platelet adhesion and coagulation factor VIII binding.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Recombinant Von Willebrand factor TARGET Recombinant Von Willebrand factor Nicoletta C Machin marketed Recombinant coagulation factor Von Willebrand factor receptor (GPIb-IX-V complex on platelets); Factor VIII binding site
Albutrepenonacog Alfa 1 UNT [IDELVION] Albutrepenonacog Alfa 1 UNT [IDELVION] National Taiwan University Hospital marketed Recombinant coagulation factor (Factor IX fusion protein) Factor IX (coagulation factor IX)
Eptacog alfa (NovoSeven) Eptacog alfa (NovoSeven) Novo Nordisk A/S marketed Recombinant coagulation factor Tissue factor (TF) / Factor X
Kogenate (BAY14-2222) Kogenate (BAY14-2222) Bayer marketed Recombinant coagulation factor VIII Coagulation factor VIII
Moroctocog alfa (AF-CC) Moroctocog alfa (AF-CC) Pfizer marketed Recombinant coagulation factor VIII Coagulation factor VIII
FIX FIX Bioverativ Therapeutics Inc. marketed Recombinant coagulation factor replacement Factor IX (coagulation cascade)
Efmoroctocog Alfa Injection [Eloctate] Efmoroctocog Alfa Injection [Eloctate] The League of Clinical Research, Russia marketed Recombinant coagulation factor VIII Coagulation factor VIII (intrinsic tenase complex)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Recombinant coagulation factor class)

  1. Baxalta now part of Shire · 2 drugs in this class
  2. AryoGen Pharmed Co. · 1 drug in this class
  3. Nicoletta C Machin · 1 drug in this class
  4. Novo Nordisk A/S · 1 drug in this class
  5. ZymoGenetics · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Recombinant Von Willebrand factor — Competitive Intelligence Brief. https://druglandscape.com/ci/recombinant-von-willebrand-factor. Accessed 2026-05-16.

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