Who are recombinant human endostatin's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): endostar+chemoradiotherapy, ramucirumab (IMC-1121B), Ramucirumab+ paclitaxel, ENDOSTAR，cisplatin, bevacizumab plus chemotherapy, Endostar continuous intravenous infusion.

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Last reviewed 2026-06-10 · How we verify

recombinant human endostatin — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

recombinant human endostatin (recombinant human endostatin) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Angiogenesis inhibitor. Area: Oncology.

marketed Angiogenesis inhibitor Endothelial cells (multiple pathways including integrin and VEGF-related mechanisms) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

recombinant human endostatin (recombinant human endostatin) — Peking University Cancer Hospital & Institute. Recombinant human endostatin inhibits angiogenesis by blocking new blood vessel formation in tumors.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
recombinant human endostatin TARGET	recombinant human endostatin	Peking University Cancer Hospital & Institute	marketed	Angiogenesis inhibitor	Endothelial cells (multiple pathways including integrin and VEGF-related mechanisms)
endostar+chemoradiotherapy	endostar+chemoradiotherapy	Second Affiliated Hospital of Xi'an Jiaotong University	marketed	Angiogenesis inhibitor	Endothelial cells; inhibits multiple angiogenic pathways
ramucirumab (IMC-1121B)	ramucirumab (IMC-1121B)	Eli Lilly and Company	phase 3	Angiogenesis inhibitor	VEGFR2
Ramucirumab+ paclitaxel	Ramucirumab+ paclitaxel	AstraZeneca	phase 3	Angiogenesis inhibitor, Microtubule inhibitor	VEGFR2
ENDOSTAR，cisplatin	ENDOSTAR，cisplatin	Jiangsu Simcere Pharmaceutical Co., Ltd.	phase 3	Angiogenesis inhibitor	Endothelial cells; inhibits VEGF-mediated angiogenesis
bevacizumab plus chemotherapy	bevacizumab plus chemotherapy	Liaoning Cancer Hospital & Institute	phase 3	Angiogenesis inhibitor	VEGF-A
Endostar continuous intravenous infusion	Endostar continuous intravenous infusion	Jiangsu Simcere Pharmaceutical Co., Ltd.	phase 3	Angiogenesis inhibitor	VEGF signaling pathway; endothelial cells

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Angiogenesis inhibitor class)

Jiangsu Simcere Pharmaceutical Co., Ltd. · 3 drugs in this class
Eli Lilly and Company · 1 drug in this class
Guangzhou Institute of Respiratory Disease · 1 drug in this class
Hoffmann-La Roche · 1 drug in this class
Liaoning Cancer Hospital & Institute · 1 drug in this class
PPD Development, LP · 1 drug in this class
Peking University Cancer Hospital & Institute · 1 drug in this class
Sanofi · 1 drug in this class
ARCAGY/ GINECO GROUP · 1 drug in this class
Second Affiliated Hospital of Xi'an Jiaotong University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). recombinant human endostatin — Competitive Intelligence Brief. https://druglandscape.com/ci/recombinant-human-endostatin. Accessed 2026-06-10.

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