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R21Matrix M — Competitive Intelligence Brief
phase 3
Recombinant protein subunit vaccine
Plasmodium falciparum circumsporozoite protein (CSP)
Infectious Disease / Immunology
Biologic
Live · refreshed every 30 min
Target snapshot
R21Matrix M (R21Matrix M) — London School of Hygiene and Tropical Medicine. R21/Matrix M is a recombinant protein subunit malaria vaccine that elicits immune responses against the Plasmodium falciparum parasite.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| R21Matrix M TARGET | R21Matrix M | London School of Hygiene and Tropical Medicine | phase 3 | Recombinant protein subunit vaccine | Plasmodium falciparum circumsporozoite protein (CSP) | |
| RSV Vaccine | RSV Vaccine | Pfizer | marketed | Recombinant protein subunit vaccine | Respiratory syncytial virus (RSV) fusion (F) glycoprotein | |
| NVX-CoV2705 Vaccine | NVX-CoV2705 Vaccine | Novavax | phase 3 | Recombinant protein subunit vaccine | SARS-CoV-2 spike protein | |
| R21/Matrix-M™ | R21/Matrix-M™ | University of Oxford | phase 3 | Recombinant protein subunit vaccine | Plasmodium falciparum circumsporozoite protein (CSP) | |
| NVX-CoV2515 | NVX-CoV2515 | Novavax | phase 3 | Recombinant protein subunit vaccine | SARS-CoV-2 spike protein | |
| Cervavac as two dose regimen | Cervavac as two dose regimen | Serum Institute of India Pvt. Ltd. | phase 3 | Recombinant protein subunit vaccine | HPV L1 capsid protein (types 16 and 18) | |
| EuCorVac-19 | EuCorVac-19 | EuBiologics Co.,Ltd | phase 3 | Recombinant protein subunit vaccine | SARS-CoV-2 spike protein (S protein) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Recombinant protein subunit vaccine class)
- Novavax · 2 drugs in this class
- London School of Hygiene and Tropical Medicine · 1 drug in this class
- Medigen Vaccine Biologics Corp. · 1 drug in this class
- EuBiologics Co.,Ltd · 1 drug in this class
- Pfizer · 1 drug in this class
- Serum Institute of India Pvt. Ltd. · 1 drug in this class
- University of Oxford · 1 drug in this class
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Cite this brief
Drug Landscape (2026). R21Matrix M — Competitive Intelligence Brief. https://druglandscape.com/ci/r21matrix-m. Accessed 2026-05-14.
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