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Protease Inhibitor/ritonavir — Competitive Intelligence Brief

Protease Inhibitor/ritonavir (Protease Inhibitor/ritonavir) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Protease inhibitor combination. Area: Infectious Disease.

phase 3 Protease inhibitor combination HIV protease Infectious Disease Small molecule Live · refreshed every 30 min

Target snapshot

Protease Inhibitor/ritonavir (Protease Inhibitor/ritonavir) — Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia. This combination inhibits HIV protease while ritonavir acts as a pharmacokinetic booster to increase protease inhibitor levels in the bloodstream.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Protease Inhibitor/ritonavir TARGET Protease Inhibitor/ritonavir Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia phase 3 Protease inhibitor combination HIV protease
ATV/r ATV/r Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections marketed HIV protease inhibitor (boosted) HIV protease
Darunavir (DRV/r) Darunavir (DRV/r) Community Research Initiative of New England marketed HIV protease inhibitor HIV protease
Maraviroc, Darunavir/r Maraviroc, Darunavir/r Catholic University of the Sacred Heart marketed Antiretroviral combination (CCR5 antagonist + protease inhibitor) CCR5 co-receptor (maraviroc); HIV protease (darunavir)
Darunavir/Ritonavir (Prezista) Darunavir/Ritonavir (Prezista) Kowa Research Institute, Inc. marketed HIV protease inhibitor HIV protease
Lopinavir/r Lopinavir/r Universidade Federal do Rio de Janeiro marketed Protease inhibitor HIV protease
PEP PEP Christopher J. McLeod marketed Protease inhibitor HIV protease

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Protease inhibitor combination class)

  1. Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia · 1 drug in this class
  2. Fundación Huésped · 1 drug in this class
  3. National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class
  4. University of Chicago · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Protease Inhibitor/ritonavir — Competitive Intelligence Brief. https://druglandscape.com/ci/protease-inhibitor-ritonavir. Accessed 2026-05-17.

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