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Protease Inhibitor/ritonavir — Competitive Intelligence Brief
phase 3
Protease inhibitor combination
HIV protease
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Protease Inhibitor/ritonavir (Protease Inhibitor/ritonavir) — Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia. This combination inhibits HIV protease while ritonavir acts as a pharmacokinetic booster to increase protease inhibitor levels in the bloodstream.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Protease Inhibitor/ritonavir TARGET | Protease Inhibitor/ritonavir | Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia | phase 3 | Protease inhibitor combination | HIV protease | |
| ATV/r | ATV/r | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | HIV protease inhibitor (boosted) | HIV protease | |
| Darunavir (DRV/r) | Darunavir (DRV/r) | Community Research Initiative of New England | marketed | HIV protease inhibitor | HIV protease | |
| Maraviroc, Darunavir/r | Maraviroc, Darunavir/r | Catholic University of the Sacred Heart | marketed | Antiretroviral combination (CCR5 antagonist + protease inhibitor) | CCR5 co-receptor (maraviroc); HIV protease (darunavir) | |
| Darunavir/Ritonavir (Prezista) | Darunavir/Ritonavir (Prezista) | Kowa Research Institute, Inc. | marketed | HIV protease inhibitor | HIV protease | |
| Lopinavir/r | Lopinavir/r | Universidade Federal do Rio de Janeiro | marketed | Protease inhibitor | HIV protease | |
| PEP | PEP | Christopher J. McLeod | marketed | Protease inhibitor | HIV protease |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Protease inhibitor combination class)
- Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia · 1 drug in this class
- Fundación Huésped · 1 drug in this class
- National Institute of Allergy and Infectious Diseases (NIAID) · 1 drug in this class
- University of Chicago · 1 drug in this class
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- Protease Inhibitor/ritonavir CI watch — RSS
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Cite this brief
Drug Landscape (2026). Protease Inhibitor/ritonavir — Competitive Intelligence Brief. https://druglandscape.com/ci/protease-inhibitor-ritonavir. Accessed 2026-05-17.
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