Last reviewed · How we verify
Surgestone — Competitive Intelligence Brief
phase 2
promegestone
Progesterone receptor, Androgen receptor
Other
Small molecule
Live · refreshed every 30 min
Target snapshot
Surgestone (PROMEGESTONE). Surgestone works by binding to the progesterone receptor, mimicking the effects of the natural hormone progesterone.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Surgestone TARGET | PROMEGESTONE | phase 2 | promegestone | Progesterone receptor, Androgen receptor | ||
| Tibolone (Livial) | Tibolone (Livial) | Wyeth is now a wholly owned subsidiary of Pfizer | marketed | Selective tissue estrogenic activity regulator (STEAR); synthetic steroid | Estrogen receptor, progesterone receptor, androgen receptor | |
| ethinyl estradiol and cyproterone acetate | ethinyl estradiol and cyproterone acetate | S.C.B. Medical College and Hospital | marketed | Combined oral contraceptive with anti-androgenic activity | Estrogen receptor, progesterone receptor, androgen receptor | |
| Add back therapy 1 (tibolone) | Add back therapy 1 (tibolone) | University of Cagliari | marketed | Selective Tissue Estrogenic Activity Regulator (STEAR); Hormone Replacement Therapy | Estrogen receptor, Progesterone receptor, Androgen receptor | |
| Tibolone plus Xiangshao granules | Tibolone plus Xiangshao granules | Peking Union Medical College Hospital | marketed | Hormone replacement therapy (HRT) / Selective tissue estrogenic activity regulator (STEAR) | Estrogen receptor, Progesterone receptor, Androgen receptor | |
| fenofibrate and tibolone | fenofibrate and tibolone | Keogh Institute for Medical Research | marketed | Fibrate + Selective Estrogen Receptor Modulator (SERM) | PPAR-α (fenofibrate); Estrogen receptor, progesterone receptor, androgen receptor (tibolone) | |
| Black Cohosh (iCR) or tibolone | Black Cohosh (iCR) or tibolone | Schaper & Bruemmer GmbH & Co KG | phase 3 | Herbal extract / Selective tissue estrogenic activity regulator (STEAR) | Serotonin receptors (Black Cohosh); estrogen receptor, progesterone receptor, androgen receptor (tibolone) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (promegestone class)
- · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- Surgestone CI watch — RSS
- Surgestone CI watch — Atom
- Surgestone CI watch — JSON
- Surgestone alone — RSS
- Whole promegestone class — RSS
Cite this brief
Drug Landscape (2026). Surgestone — Competitive Intelligence Brief. https://druglandscape.com/ci/promegestone. Accessed 2026-06-10.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing