Who are Preservative-free artificial tears's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Refresh Endura, Hyaluronic acid 0.05% & Ectoine 2.0%, Artificial tear eye drop, artificial tear therapy, Non-Lipid Artificial Tear, Rohto (r) Hydra.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Preservative-free artificial tears — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Preservative-free artificial tears (Preservative-free artificial tears) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Ophthalmic lubricant. Area: Ophthalmology.

marketed Ophthalmic lubricant Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

Preservative-free artificial tears (Preservative-free artificial tears) — University Hospital, Ghent. Preservative-free artificial tears lubricate and hydrate the ocular surface to relieve symptoms of dry eye disease.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class
Preservative-free artificial tears TARGET	Preservative-free artificial tears	University Hospital, Ghent	marketed	Ophthalmic lubricant
Refresh Endura	Refresh Endura	Federal University of São Paulo	marketed	Ophthalmic lubricant / Artificial tear
Hyaluronic acid 0.05% & Ectoine 2.0%	Hyaluronic acid 0.05% & Ectoine 2.0%	Michael Marchand, MD	marketed	Ophthalmic lubricant and protectant
Artificial tear eye drop	Artificial tear eye drop	Nguyen Viet Giap	marketed	Ophthalmic lubricant
artificial tear therapy	artificial tear therapy	Tianjin Medical University Eye Hospital	marketed	Ophthalmic lubricant
Non-Lipid Artificial Tear	Non-Lipid Artificial Tear	University of Seville	marketed	Artificial tear / Ophthalmic lubricant
Rohto (r) Hydra	Rohto (r) Hydra	ORA, Inc.	marketed	Ophthalmic lubricant / Artificial tear

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Ophthalmic lubricant class)

Allergan · 1 drug in this class
Bausch & Lomb Incorporated · 1 drug in this class
Massachusetts Eye and Ear Infirmary · 1 drug in this class
National University of Malaysia · 1 drug in this class
Nguyen Viet Giap · 1 drug in this class
Ophthalmic Consultants of Long Island · 1 drug in this class
Tianjin Medical University Eye Hospital · 1 drug in this class
Universidad Nacional de Colombia · 1 drug in this class
University Hospital, Ghent · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Preservative-free artificial tears — Competitive Intelligence Brief. https://druglandscape.com/ci/preservative-free-artificial-tears. Accessed 2026-05-16.

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