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Refresh Endura
Refresh Endura is an ophthalmic lubricant that provides sustained hydration and protection to the ocular surface.
Refresh Endura is an ophthalmic lubricant that provides sustained hydration and protection to the ocular surface. Used for Dry eye syndrome / Keratoconjunctivitis sicca.
At a glance
| Generic name | Refresh Endura |
|---|---|
| Also known as | Castor oil |
| Sponsor | Federal University of São Paulo |
| Drug class | Ophthalmic lubricant / Artificial tear |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | FDA-approved |
Mechanism of action
This product is designed as an artificial tear formulation intended to relieve dry eye symptoms by maintaining moisture on the cornea and conjunctiva. It likely contains demulcents and/or viscosity-enhancing agents to extend contact time with the ocular surface and reduce tear evaporation.
Approved indications
- Dry eye syndrome / Keratoconjunctivitis sicca
Common side effects
- Ocular irritation
- Blurred vision
- Eye discomfort
Key clinical trials
- Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease (PHASE4)
- The Effects of Cyclosporin A in a Low Humidity Environment, on the Ocular Surface (NA)
- Topical Cyclosporine vs. Placebo for Epiphora Associated With Docetaxel (PHASE2)
- Safety and Efficacy Study of Cyclosporine Ophthalmic Emulsion in Post-LASIK Patients (PHASE2)
- Efficacy of Topical Cyclosporin for Ocular Rosacea (PHASE4)
- Oasys vs. Extreme H20 Xtra 59 (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Refresh Endura CI brief — competitive landscape report
- Refresh Endura updates RSS · CI watch RSS
- Federal University of São Paulo portfolio CI