Who are Premarin vaginal estrogen cream's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Estrogen vaginal cream, Postmenopausal, topical vaginal estrogen cream.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Premarin vaginal estrogen cream — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Premarin vaginal estrogen cream (Premarin vaginal estrogen cream) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Estrogen replacement therapy (topical). Area: Gynecology / Menopause.

marketed Estrogen replacement therapy (topical) Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) Gynecology / Menopause Small molecule Live · refreshed every 30 min

Target snapshot

Premarin vaginal estrogen cream (Premarin vaginal estrogen cream) — Medstar Health Research Institute. Premarin vaginal cream delivers conjugated estrogens directly to vaginal tissue to restore estrogen levels and relieve symptoms of vaginal atrophy and menopausal urogenital symptoms.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Premarin vaginal estrogen cream TARGET	Premarin vaginal estrogen cream	Medstar Health Research Institute	marketed	Estrogen replacement therapy (topical)	Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ)
Estrogen vaginal cream	Estrogen vaginal cream	The University of Texas Health Science Center, Houston	marketed	Estrogen replacement therapy (topical)	Estrogen receptor alpha and beta
Postmenopausal, topical vaginal estrogen cream	Postmenopausal, topical vaginal estrogen cream	The University of Texas Medical Branch, Galveston	marketed	Estrogen replacement therapy (topical)	Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Estrogen replacement therapy (topical) class)

Medstar Health Research Institute · 1 drug in this class
The University of Texas Health Science Center, Houston · 1 drug in this class
The University of Texas Medical Branch, Galveston · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Premarin vaginal estrogen cream — Competitive Intelligence Brief. https://druglandscape.com/ci/premarin-vaginal-estrogen-cream. Accessed 2026-05-16.

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