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Pregabalin Release Tablets — Competitive Intelligence Brief
phase 3
Gabapentinoid; anticonvulsant; anxiolytic
Voltage-gated calcium channel alpha-2-delta-1 subunit
Neurology; Pain Management; Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
Pregabalin Release Tablets (Pregabalin Release Tablets) — Jiangsu HengRui Medicine Co., Ltd.. Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Pregabalin Release Tablets TARGET | Pregabalin Release Tablets | Jiangsu HengRui Medicine Co., Ltd. | phase 3 | Gabapentinoid; anticonvulsant; anxiolytic | Voltage-gated calcium channel alpha-2-delta-1 subunit | |
| Neurontin | gabapentin | Generic (originally Parke-Davis/Pfizer) | marketed | Gabapentinoid (anticonvulsant/neuropathic pain agent) | Large neutral amino acids transporter small subunit 1, Adenosine receptor A1, Alpha-2A adrenergic receptor | 1993-12-30 |
| Gabapentin immediate release | Gabapentin immediate release | Theresa Zesiewicz, MD | marketed | Anticonvulsant; gabapentinoid | Voltage-gated calcium channel alpha-2-delta subunit | |
| trazodone, pregabalin | trazodone, pregabalin | Universidad de Granada | marketed | Combination anxiolytic/analgesic (serotonin antagonist and reuptake inhibitor + gabapentinoid) | 5-HT2A receptor, serotonin transporter (SERT), alpha-2-delta calcium channel subunit | |
| pregabalin capsules | pregabalin capsules | AstraZeneca | marketed | Gabapentinoid; anticonvulsant; anxiolytic | Alpha-2-delta-1 subunit of voltage-gated calcium channels | |
| transdermal fentanyl matrix, gabapentin | transdermal fentanyl matrix, gabapentin | Seoul National University Hospital | marketed | Opioid analgesic + gabapentinoid | Mu-opioid receptor (fentanyl); alpha-2-delta calcium channel subunit (gabapentin) | |
| Pregabalin and dexmedetomidine | Pregabalin and dexmedetomidine | Wonkwang University Hospital | marketed | Combination analgesic/sedative (gabapentinoid + alpha-2 agonist) | Alpha-2-delta calcium channel subunit (pregabalin); alpha-2 adrenergic receptor (dexmedetomidine) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Gabapentinoid; anticonvulsant; anxiolytic class)
- AstraZeneca · 1 drug in this class
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences · 1 drug in this class
- Hawler Medical University · 1 drug in this class
- Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Pregabalin Release Tablets — Competitive Intelligence Brief. https://druglandscape.com/ci/pregabalin-release-tablets. Accessed 2026-05-14.
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