Who are Placebo to Ondansetron's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Trintellix, Ondansetron orodispersible film once, Zofran inj.+Zofran tab., Kytril inj.+Kytril tab., Ondansetron (ODT), Venlafaxine XR + Mirtazapine.

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Last reviewed 2026-05-17 · How we verify

Placebo to Ondansetron — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Placebo to Ondansetron (Placebo to Ondansetron) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: 5-HT3 receptor antagonist. Area: Oncology, Gastroenterology, Anesthesia.

phase 3 5-HT3 receptor antagonist 5-HT3 receptor Oncology, Gastroenterology, Anesthesia Small molecule Live · refreshed every 30 min

Target snapshot

Placebo to Ondansetron (Placebo to Ondansetron) — Helsinn Healthcare SA. Ondansetron is a selective 5-HT3 receptor antagonist that blocks serotonin signaling in the chemoreceptor trigger zone and gastrointestinal tract to prevent nausea and vomiting.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Placebo to Ondansetron TARGET	Placebo to Ondansetron	Helsinn Healthcare SA	phase 3	5-HT3 receptor antagonist	5-HT3 receptor
Trintellix	vortioxetine	Takeda	marketed	Serotonin modulator and stimulator (SMS); SSRI-like agent	Serotonin transporter (SERT); 5-HT3 receptor; 5-HT1A receptor	2013-01-01
Ondansetron orodispersible film once	Ondansetron orodispersible film once	Chongqing University Cancer Hospital	marketed	5-HT3 receptor antagonist	5-HT3 receptor
Zofran inj.+Zofran tab.	Zofran inj.+Zofran tab.	LG Life Sciences	marketed	5-HT3 receptor antagonist	5-HT3 receptor
Kytril inj.+Kytril tab.	Kytril inj.+Kytril tab.	LG Life Sciences	marketed	5-HT3 receptor antagonist	5-HT3 receptor
Ondansetron (ODT)	Ondansetron (ODT)	MonoSol Rx	marketed	5-HT3 receptor antagonist	5-HT3 receptor
Venlafaxine XR + Mirtazapine	Venlafaxine XR + Mirtazapine	National Institute of Mental Health (NIMH)	marketed	Antidepressant combination (SNRI + NaSSA)	Serotonin transporter, norepinephrine transporter, alpha-2 adrenergic receptors, 5-HT2 receptors, 5-HT3 receptors

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (5-HT3 receptor antagonist class)

Helsinn Healthcare SA · 4 drugs in this class
LG Life Sciences · 3 drugs in this class
University of Malaya · 2 drugs in this class
GlaxoSmithKline · 1 drug in this class
Hamad Medical Corporation · 1 drug in this class
Eye & ENT Hospital of Fudan University · 1 drug in this class
Instituto Mexicano del Seguro Social · 1 drug in this class
Chongqing University Cancer Hospital · 1 drug in this class
Merck Sharp & Dohme LLC · 1 drug in this class
MonoSol Rx · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Placebo to Ondansetron — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-to-ondansetron. Accessed 2026-05-17.

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