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Placebo to Mepolizumab — Competitive Intelligence Brief

Placebo to Mepolizumab (Placebo to Mepolizumab) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: IL-5 inhibitor. Area: Immunology.

phase 3 IL-5 inhibitor IL-5 Immunology Biologic Live · refreshed every 30 min

Target snapshot

Placebo to Mepolizumab (Placebo to Mepolizumab) — AstraZeneca. Mepolizumab is an interleukin-5 (IL-5) inhibitor that blocks the action of IL-5, a cytokine involved in the production and survival of eosinophils.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Placebo to Mepolizumab TARGET Placebo to Mepolizumab AstraZeneca phase 3 IL-5 inhibitor IL-5
EXDENSUR DEPEMOKIMAB-ULAA GLAXOSMITHKLINE LLC marketed IL-5
Asthma therapies Asthma therapies Genentech, Inc. marketed Monoclonal antibodies (multiple agents with different targets) IgE, IL-5, IL-4 receptor alpha (varies by specific agent)
anti IL5 receptor antibodies anti IL5 receptor antibodies Scarlata, Simone, M.D. marketed IL-5 receptor antagonist monoclonal antibody IL-5 receptor (IL-5R)
Mepolizumab Injection [Nucala] Mepolizumab Injection [Nucala] KU Leuven marketed IL-5 antagonist monoclonal antibody IL-5 (Interleukin-5)
Benralizumab Prefilled Syringe Benralizumab Prefilled Syringe Nantes University Hospital marketed IL-5 receptor antagonist monoclonal antibody IL-5 receptor alpha (IL-5Rα)
Fasenra® Fasenra® AstraZeneca marketed IL-5 receptor antagonist monoclonal antibody IL-5Rα (interleukin-5 receptor alpha)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (IL-5 inhibitor class)

  1. AstraZeneca · 1 drug in this class
  2. GlaxoSmithKline · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Placebo to Mepolizumab — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-to-mepolizumab. Accessed 2026-05-18.

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