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Placebo to BIC/FTC/TAF — Competitive Intelligence Brief

Placebo to BIC/FTC/TAF (Placebo to BIC/FTC/TAF) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antiretroviral combination (INSTI + NRTI + NtRTI). Area: Infectious Disease / Virology.

phase 3 Antiretroviral combination (INSTI + NRTI + NtRTI) HIV integrase, HIV reverse transcriptase Infectious Disease / Virology Small molecule Live · refreshed every 30 min

Target snapshot

Placebo to BIC/FTC/TAF (Placebo to BIC/FTC/TAF) — Merck Sharp & Dohme LLC. BIC/FTC/TAF is a fixed-dose combination of three antiretroviral agents that inhibit HIV reverse transcriptase and integrase to suppress viral replication.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Placebo to BIC/FTC/TAF TARGET Placebo to BIC/FTC/TAF Merck Sharp & Dohme LLC phase 3 Antiretroviral combination (INSTI + NRTI + NtRTI) HIV integrase, HIV reverse transcriptase
Switch to B/F/TAF Switch to B/F/TAF University of Nairobi marketed Antiretroviral combination (integrase inhibitor + nucleoside/nucleotide reverse transcriptase inhibitors) HIV integrase, HIV reverse transcriptase
Raltegravir and Abacavir/Lamivudine Raltegravir and Abacavir/Lamivudine Denver Infectious Disease Consultants, PLLC marketed Antiretroviral combination (INSTI + NRTI) HIV integrase, HIV reverse transcriptase
Bictegravir / Emtricitabine / Tenofovir Alafenamide Pill Bictegravir / Emtricitabine / Tenofovir Alafenamide Pill Charlotte-Paige Rolle, MD marketed Antiretroviral combination (integrase inhibitor + nucleoside reverse transcriptase inhibitors) HIV integrase, HIV reverse transcriptase
Biktarvy Tab Biktarvy Tab Southampton Healthcare, Inc. marketed Antiretroviral combination therapy (integrase inhibitor + nucleoside/nucleotide reverse transcriptase inhibitors) HIV integrase, HIV reverse transcriptase, CCR5 co-receptor
DTG/3TC/ABC + ELV/COBI/FTC/TAF DTG/3TC/ABC + ELV/COBI/FTC/TAF Fundacion SEIMC-GESIDA marketed Antiretroviral combination therapy (integrase inhibitor + nucleoside/nucleotide reverse transcriptase inhibitors) HIV integrase, HIV reverse transcriptase
Raltegravir, tenofovir/emtricitabine Raltegravir, tenofovir/emtricitabine University of California, San Francisco marketed Antiretroviral combination therapy (integrase inhibitor + nucleoside/nucleotide reverse transcriptase inhibitors) HIV integrase, HIV reverse transcriptase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antiretroviral combination (INSTI + NRTI + NtRTI) class)

  1. Merck Sharp & Dohme LLC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Placebo to BIC/FTC/TAF — Competitive Intelligence Brief. https://druglandscape.com/ci/placebo-to-bic-ftc-taf. Accessed 2026-05-16.

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