Who are Phentolamine Opthalmic Solution 0.75%'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): OraVerse Injectable Product, Phentolamine Ophthalmic Solution 0.75%.

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Last reviewed 2026-05-18 · How we verify

Phentolamine Opthalmic Solution 0.75% — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Phentolamine Opthalmic Solution 0.75% (Phentolamine Opthalmic Solution 0.75%) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Alpha-adrenergic antagonist. Area: Ophthalmology.

phase 3 Alpha-adrenergic antagonist Alpha-1 adrenergic receptor, Alpha-2 adrenergic receptor Ophthalmology Small molecule Live · refreshed every 30 min

Target snapshot

Phentolamine Opthalmic Solution 0.75% (Phentolamine Opthalmic Solution 0.75%) — Ocuphire Pharma, Inc.. Phentolamine is an alpha-adrenergic receptor antagonist that blocks norepinephrine signaling in the eye to reduce pupil dilation and improve aqueous humor outflow.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Phentolamine Opthalmic Solution 0.75% TARGET	Phentolamine Opthalmic Solution 0.75%	Ocuphire Pharma, Inc.	phase 3	Alpha-adrenergic antagonist	Alpha-1 adrenergic receptor, Alpha-2 adrenergic receptor
OraVerse Injectable Product	OraVerse Injectable Product	sara nabil	phase 3	Alpha-adrenergic antagonist	Alpha-1 and alpha-2 adrenergic receptors
Phentolamine Ophthalmic Solution 0.75%	Phentolamine Ophthalmic Solution 0.75%	Ocuphire Pharma, Inc.	phase 3	Alpha-adrenergic antagonist	Alpha-1 and alpha-2 adrenergic receptors

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Alpha-adrenergic antagonist class)

Ocuphire Pharma, Inc. · 2 drugs in this class
sara nabil · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Phentolamine Opthalmic Solution 0.75% — Competitive Intelligence Brief. https://druglandscape.com/ci/phentolamine-opthalmic-solution-0-75. Accessed 2026-05-18.

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